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[FZJ-2025-05029]
Abstract
Caspari, B. ; Bittner, N. ; Miller, T. ; et al
Microarchitectural differences between White Matter Lesions and Normal-Appearing White Matter across Arterial Territories: Insights from Neurite Orientation Dispersion and Density Imaging
2025Aging and Cognition Conference, PaviaPavia, Italy, 7 May 2025 - 10 May 20252025-05-072025-05-10
White Matter Lesions (WML) are linked to aging and vascular risk factors, while their microstructural mechanisms remain largely unclear. Using Neurite Orientation Dispersion and Density Imaging (NODDI), we investigated microarchitectural properties in WML in 915 participants (47% female, ages 18-85) from the population-based 1000BRAINS study.Microstructural properties, i.e. [...]
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