Contributions to a conference proceedings

Introduction: Serotonergic 5-HT2A receptors are widely expressed in the cortex and other forebrain structures, where they play a crucial role for cognitive and emotional processes. Dysfunction of these receptors is associated with various neuropsychiatric and neurodegenerative disorders, making them an attractive target for positron emission tomography (PET) imaging. [...]

Introduction: Due to its favorable decay properties, the α-emitter Astatine-211 (211At) is particularly promising for treatment of tumors, especially (micro-)metastases resistant to conventional β-therapy. The radionuclide has experienced increased interest, which results in an unmet need for 211At-labeled radiopharmaceuticals. [...]

Introduction: Radiolabeled (het)aryl fluorosulfates [1] and, in some cases, sulfamoyl fluorides [2] can be efficiently prepared via SuFEx-based 18F/19F isotopic exchange. However, application of this approach for the preparation of aliphatic sulfamoyl [18F]fluorides ([18F]ASAFs) has resulted in unacceptably low molar activities (Am). [...]