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Letzte Einträge:
2019-06-19
14:20
[FZJ-2019-03493] Journal Article
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Identification of Surf1 as an assembly factor of the cytochrome bc1-aa3 supercomplex of Actinobacteria
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ddc:570
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2019-06-19
13:16
OpenAccess [FZJ-2019-03491] Journal Article
et al
Pseudomonas putida rDNA is a favored site for the expression of biosynthetic genes
Since high-value bacterial secondary metabolites, including antibiotics, are often naturally produced in only low amounts, their efficient biosynthesis typically requires the transfer of entire metabolic pathways into suitable bacterial hosts like Pseudomonas putida. Stable maintenance and sufficient expression of heterologous pathway-encoding genes in host microbes, however, still remain key challenges. [...]
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ddc:600
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2019-06-19
11:37
OpenAccess [FZJ-2019-03487] Journal Article
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Comparison of first-principles methods to extract magnetic parameters in ultrathin films: Co/Pt(111)
We compare three distinct computational approaches based on first-principles calculations within density functional theory to explore the magnetic exchange and the Dzyaloshinskii-Moriya interactions (DMI) of a Co monolayer on Pt(111), namely, (i) the method of infinitesimal rotations of magnetic moments based on the Korringa-Kohn-Rostoker (KKR) Green function method, (ii) the generalized Bloch theorem applied to spiraling magnetic structures and (iii) supercell calculations with noncollinear magnetic moments, the latter two being based on the full-potential linearized augmented plane wave (FLAPW) method. In particular, we show that the magnetic interaction parameters entering micromagnetic models describing the long-wavelength deviations from the ferromagnetic state might be different from those calculated for fast rotating magnetic structures, as they are obtained by using (necessarily rather small) supercell or large spin-spiral wave vectors. [...]
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ddc:530
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2019-06-17
15:31
OpenAccess [FZJ-2019-03439] Journal Article
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High-Yield Production of 4-Hydroxybenzoate From Glucose or Glycerol by an Engineered Pseudomonas taiwanensis VLB120
Aromatic compounds such as 4-hydroxybenzoic acid are broadly applied in industry for a myriad of applications used in everyday life. However, their industrial production currently relies heavily on fossil resources and involves environmentally unfriendly production conditions, thus creating the need for more sustainable biotechnological alternatives. [...]
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ddc:570
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2019-06-17
13:19
[FZJ-2019-03431] Journal Article
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Bilingualism and “Brain Reserve”: A Matter of Age
There is a lively debate whether bilingualism as a state of permanent cognitive control contributes to so-called brain reserve, thus delaying the onset of symptoms associated with neurodegeneration by up to 5 years. Here, we address this question in a large-scale (n=399) population-based study. [...]
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ddc:610
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2019-06-17
08:05
[FZJ-2019-03402] Journal Article
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Scatter Correction based on GPU-accelerated Full Monte Carlo Simulation for Brain PET/MRI
ddc:620
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2019-06-16
10:09
[FZJ-2019-03398] Journal Article
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Branched alkyldimethylamine oxide surfactants: An effective strategy for the design of high concentration/low viscosity surfactant formulations
HypothesisThe rational design of branched-tail surfactants is a suitable strategy to obtain low-viscosity surfactant-rich isotropic aqueous mixtures with negligible effects on biodegradability. This opens a way to the design of concentrated (“water-free”) surfactant formulations, highly attractive for their ecological and economic benefits.ExperimentsThe aggregation behaviour of N,N-dimethyl-2-propylheptan-1-amine oxide (C10DAO-branched) in aqueous mixtures is investigated across the entire composition range by polarized optical microscopy, small angle X-ray and neutron scattering, electron paramagnetic resonance, and pulse-gradient stimulated echo nuclear magnetic resonance. [...]
ddc:540
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2019-06-14
11:14
[FZJ-2019-03393] Journal Article
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Keramische Membranen: Materialien – Bauteile – potenzielle Anwendungen
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ddc:660
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2019-06-13
13:07
[FZJ-2019-03386] Journal Article

PACKMOL-Memgen: A Simple-To-Use, Generalized Workflow for Membrane-Protein–Lipid-Bilayer System Building
We present PACKMOL-Memgen, a simple-to-use, generalized workflow for automated building of membrane-protein–lipid-bilayer systems based on open-source tools including Packmol, memembed, pdbremix, and AmberTools. Compared with web-interface-based related tools, PACKMOL-Memgen allows setup of multiple configurations of a system in a user-friendly and efficient manner within minutes. [...]
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ddc:540
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2019-06-13
13:04
[FZJ-2019-03385] Journal Article
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Novel Fluorescent Cyclic Nucleotide Derivatives to Study CNG and HCN Channel Function
Biophysical journal NA, S0006349519303856 () [10.1016/j.bpj.2019.05.006]
A highly specific molecular interaction of diffusible ligands with their receptors belongs to the key processes in cellular signaling. Because an appropriate method to monitor the unitary binding events is still missing, most of our present knowledge is based on ensemble signals recorded from a big number of receptors, such as ion currents or fluorescence changes of suitably labeled receptors, and reasoning from these data to the ligand binding. [...]
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ddc:570
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