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@ARTICLE{Zare:1005158,
      author       = {Zare, Iman and Yaraki, Mohammad Tavakkoli and Speranza,
                      Giorgio and Najafabadi, Alireza Hassani and
                      Shourangiz-Haghighi, Alireza and Nik, Amirala Bakhshian and
                      Manshian, Bella B. and Saraiva, Cláudia and Soenen, Stefaan
                      J. and Kogan, Marcelo J. and Lee, Jee Woong and Apollo,
                      Nicholas V. and Bernardino, Liliana and Araya, Eyleen and
                      Mayer, Dirk and Mao, Guangzhao and Hamblin, Michael R.},
      title        = {{G}old nanostructures: synthesis, properties, and
                      neurological applications},
      journal      = {Chemical Society reviews},
      volume       = {51},
      issn         = {0306-0012},
      address      = {London},
      publisher    = {Soc.},
      reportid     = {FZJ-2023-01346},
      pages        = {2601-2680},
      year         = {2022},
      note         = {Bitte Post-print ergänzen},
      abstract     = {Recent advances in technology are expected to increase our
                      current understanding of neuroscience. Nanotechnology and
                      nanomaterials can alter and control neural functionality in
                      both in vitro and in vivo experimental setups. The
                      intersection between neuroscience and nanoscience may
                      generate long-term neural interfaces adapted at the
                      molecular level. Owing to their intrinsic physicochemical
                      characteristics, gold nanostructures (GNSs) have received
                      much attention in neuroscience, especially for combined
                      diagnostic and therapeutic (theragnostic) purposes. GNSs
                      have been successfully employed to stimulate and monitor
                      neurophysiological signals. Hence, GNSs could provide a
                      promising solution for the regeneration and recovery of
                      neural tissue, novel neuroprotective strategies, and
                      integrated implantable materials. This review covers the
                      broad range of neurological applications of GNS-based
                      materials to improve clinical diagnosis and therapy.
                      Sub-topics include neurotoxicity, targeted delivery of
                      therapeutics to the central nervous system (CNS),
                      neurochemical sensing, neuromodulation, neuroimaging,
                      neurotherapy, tissue engineering, and neural regeneration.
                      It focuses on core concepts of GNSs in neurology, to
                      circumvent the limitations and significant obstacles of
                      innovative approaches in neurobiology and neurochemistry,
                      including theragnostics. We will discuss recent advances in
                      the use of GNSs to overcome current bottlenecks and tackle
                      technical and conceptual challenges.},
      cin          = {IBI-3},
      ddc          = {540},
      cid          = {I:(DE-Juel1)IBI-3-20200312},
      pnm          = {5241 - Molecular Information Processing in Cellular Systems
                      (POF4-524)},
      pid          = {G:(DE-HGF)POF4-5241},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {35234776},
      UT           = {WOS:000763005100001},
      doi          = {10.1039/D1CS01111A},
      url          = {https://juser.fz-juelich.de/record/1005158},
}