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@ARTICLE{Murmiliuk:1005333,
author = {Murmiliuk, Anastasiia and Hladysh, Sviatoslav and Filippov,
Sergey K. and Stepanek, Miroslav},
title = {{C}omprehensive {M}ultidimensional {C}haracterization of
{P}olyelectrolytes and {I}nterpolyelectrolyte {C}omplexes in
{A}queous {S}olutions},
journal = {Reviews and advances in chemistry},
volume = {12},
number = {3},
issn = {2634-8276},
address = {[Road Town, Tortola]},
publisher = {Pleiades Publishing, Ltd},
reportid = {FZJ-2023-01442},
pages = {163 - 177},
year = {2022},
abstract = {In this paper we give the overview of our latest results on
the complexation between polyelectrolytes and oppositely
charged low-molar mass species, proteins, homopolymers and
block copolymers. First, we review the results on the study
of the interaction of polythiophene-based polycations with
phosphonium and ammonium pendants and their complexation
with negatively charged multivalent species followed by
fluorescence quenching. We proved that multivalent solutes
bind to polyelectrolyte stronger than to previously studied
polythiophene, thus, allowing for their application as
luminescence sensors. Secondly, we investigated the
co-assembly of polyanion with double hydrophilic block
copolymer composed of polycationic block and neutral
hydrophilic block and followed the complex formation by
quenching of fluorescence of the indicator attached to the
end of polyanion chain. We discovered that the formed
interpolyelectrolyte (IPEC) core of core/shell micelles
remains dynamical even after equilibrium was reached thus
making such systems suitable materials for targeted delivery
of multivalent species. In addition, the formation of
micelles with fluid cores was observed as a result of
self-assembly of di- and triblock polyelectrolytes
containing a hydrophobic block with low glass transition
temperature and a positively charged block. We proved their
ability to encapsulate and release hydrophobic species from
the soft core upon dilution. Moreover, we confirmed their
ability to complex with multivalent negatively charged
species. The morphology of the formed complex strongly
depends on ionic strength: the aggregates formed by micelles
bonded at the periphery disrupt with increasing salt
concentration and a part of multivalent ions releases into
solution. Finally, the multilayered nanoparticles with both
soft hydrophobic and IPEC layers were designed by
co-assembly between core/shell micelles with a soft core and
a positively charged shell, and block polyelectrolyte
composed of polyanion and neutral hydrophilic blocks. We
showed that the morphology of the particles and the charge
of IPEC layer of such multicompartment nanostructures can be
controlled by the ratio of oppositely charged monomeric
units.},
cin = {JCNS-4 / JCNS-FRM-II / MLZ},
cid = {I:(DE-Juel1)JCNS-4-20201012 /
I:(DE-Juel1)JCNS-FRM-II-20110218 / I:(DE-588b)4597118-3},
pnm = {6G4 - Jülich Centre for Neutron Research (JCNS) (FZJ)
(POF4-6G4) / 632 - Materials – Quantum, Complex and
Functional Materials (POF4-632)},
pid = {G:(DE-HGF)POF4-6G4 / G:(DE-HGF)POF4-632},
experiment = {EXP:(DE-MLZ)NOSPEC-20140101},
typ = {PUB:(DE-HGF)16},
doi = {10.1134/S263482762260013X},
url = {https://juser.fz-juelich.de/record/1005333},
}