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@INPROCEEDINGS{Tan:1005516,
author = {Tan, Zihan},
title = {{Q}uasi-two-dimensional protein dispersions:{F}rom
monolayers with competing interactions to a
protein-membrane-cytosol model of neuronal signal
transduction},
school = {TU Berlin},
reportid = {FZJ-2023-01516},
year = {2023},
abstract = {I first discuss the phase behavior, hexagonal clustering,
and resultant intermediate-range structure order (IRO) of
quasi-two-dimensional (Q2D) protein dispersions with
competing short-range attractive (SA) and long-range
repulsive (LR) interactions. Later on, in such Q2D-SALR
systems, using Langevin dynamics and multiparticle collision
dynamics (MPC), I address the questions regarding self- and
collective diffusion, non-Gaussian dynamics, and
(time-dependent) hydrodynamic interactions (HIs). At last, I
present our modeling work on the lateral diffusion of
membrane receptor proteins. From a top-down approach, we
build a mesoscopic protein-membrane-cytosol model by
extending MPC algorithm to layered binary fluids with
viscosity contrast. In addition, lipid crowding effects are
included to capture the viscoelasticity nature of biological
membranes. This model is applied to study the diffusion of a
G-protein coupled receptor protein with a dumbbell shape.},
month = {Mar},
date = {2023-03-17},
organization = {Vortrag im Seminar Statistische Physik
weicher Materie und biologischer
Systeme, Berlin (Germany), 17 Mar 2023
- 17 Mar 2023},
subtyp = {Invited},
cin = {IAS-5 / INM-9},
cid = {I:(DE-Juel1)IAS-5-20120330 / I:(DE-Juel1)INM-9-20140121},
pnm = {5241 - Molecular Information Processing in Cellular Systems
(POF4-524)},
pid = {G:(DE-HGF)POF4-5241},
typ = {PUB:(DE-HGF)31},
url = {https://juser.fz-juelich.de/record/1005516},
}