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@ARTICLE{Kong:1005642,
author = {Kong, Ru and Tan, Yan Rui and Wulan, Naren and Ooi, Leon Qi
Rong and Farahibozorg, Seyedeh-Rezvan and Harrison, Samuel
and Bijsterbosch, Janine D. and Bernhardt, Boris C. and
Eickhoff, Simon and Yeo, B. T. Thomas},
title = {{C}omparison {B}etween {G}radients and {P}arcellations for
{F}unctional {C}onnectivity {P}rediction of {B}ehavior},
journal = {NeuroImage},
volume = {273},
issn = {1053-8119},
address = {Orlando, Fla.},
publisher = {Academic Press},
reportid = {FZJ-2023-01585},
pages = {120044 -},
year = {2023},
abstract = {Resting-state functional connectivity (RSFC) is widely used
to predict behavioral measures. To predict behavioral
measures, representing RSFC with parcellations and gradients
are the two most popular approaches. Here, we compare
parcellation and gradient approaches for RSFC-based
prediction of a broad range of behavioral measures in the
Human Connectome Project (HCP) and Adolescent Brain
Cognitive Development (ABCD) datasets. Among the
parcellation approaches, we consider group-average
“hard” parcellations (Schaefer et al., 2018),
individual-specific “hard” parcellations (Kong et al.,
2021a), and an individual-specific “soft” parcellation
(spatial independent component analysis with dual
regression; Beckmann et al., 2009). For gradient approaches,
we consider the well-known principal gradients (Margulies et
al., 2016) and the local gradient approach that detects
local RSFC changes (Laumann et al., 2015). Across two
regression algorithms, individual-specific hard-parcellation
performs the best in the HCP dataset, while the principal
gradients, spatial independent component analysis and
group-average “hard” parcellations exhibit similar
performance. On the other hand, principal gradients and all
parcellation approaches perform similarly in the ABCD
dataset. Across both datasets, local gradients perform the
worst. Finally, we find that the principal gradient approach
requires at least 40 to 60 gradients to perform as well as
parcellation approaches. While most principal gradient
studies utilize a single gradient, our results suggest that
incorporating higher order gradients can provide significant
behaviorally relevant information. Future work will consider
the inclusion of additional parcellation and gradient
approaches for comparison.},
cin = {INM-7},
ddc = {610},
cid = {I:(DE-Juel1)INM-7-20090406},
pnm = {5252 - Brain Dysfunction and Plasticity (POF4-525)},
pid = {G:(DE-HGF)POF4-5252},
typ = {PUB:(DE-HGF)16},
pubmed = {36940760},
UT = {WOS:000981253100001},
doi = {10.1016/j.neuroimage.2023.120044},
url = {https://juser.fz-juelich.de/record/1005642},
}