TY  - THES
AU  - Rama, Ramya
TI  - Morphological and functional characterization of layer 5 neurons in rat medial prefrontal cortex, their synaptic microcircuitry and serotonin modulation
VL  - 267
PB  - RWTH Aachen University
VL  - Dissertation
CY  - Jülich
M1  - FZJ-2023-01724
SN  - 978-3-95806-688-5
T2  - Schriften des Forschungszentrums Jülich Reihe Schlüsseltechnologien / Key Technologies
SP  - 116
PY  - 2023
N1  - Dissertation, RWTH Aachen University, 2022
AB  - Medial prefrontal cortex (Cortex praefrontalis medialis, mPFC) is a part of the association cortex that serves to process and integrate synaptic inputs from sensory and motor cortical areas. The mPFC plays important roles in numerous cognitive processes, such as emotional processing, executive function, decision making, spatial orientation, long-term memory and impulse control. Compared to other cortical areas, the mPFC has a particularly high density of serotonergic axons which originate from the dorsal and medial raphe nuclei; they play a crucial role in regulating the development and function of the neocortex. For this reason, a basic knowledge of the role of serotonin (5-HT) and its receptors (5-HTRs) function in the mPFC in modulating cortical activity is crucial.
LB  - PUB:(DE-HGF)3 ; PUB:(DE-HGF)11
DO  - DOI:10.34734/FZJ-2023-01724
UR  - https://juser.fz-juelich.de/record/1006583
ER  -