001006880 001__ 1006880
001006880 005__ 20240222203104.0
001006880 0247_ $$2doi$$a10.1038/s41467-023-37746-9
001006880 0247_ $$2Handle$$a2128/34332
001006880 0247_ $$2pmid$$a37059718
001006880 0247_ $$2WOS$$aWOS:000969250300022
001006880 037__ $$aFZJ-2023-01912
001006880 082__ $$a500
001006880 1001_ $$0P:(DE-Juel1)181012$$aJunglas, Benedikt$$b0$$ufzj
001006880 245__ $$aSynDLP is a dynamin-like protein of Synechocystis sp. PCC 6803 with eukaryotic features
001006880 260__ $$a[London]$$bNature Publishing Group UK$$c2023
001006880 3367_ $$2DRIVER$$aarticle
001006880 3367_ $$2DataCite$$aOutput Types/Journal article
001006880 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1708594930_13909
001006880 3367_ $$2BibTeX$$aARTICLE
001006880 3367_ $$2ORCID$$aJOURNAL_ARTICLE
001006880 3367_ $$00$$2EndNote$$aJournal Article
001006880 520__ $$aDynamin-like proteins are membrane remodeling GTPases with well-understood functions in eukaryotic cells. However, bacterial dynamin-like proteins are still poorly investigated. SynDLP, the dynamin-like protein of the cyanobacterium Synechocystis sp. PCC 6803, forms ordered oligomers in solution. The 3.7 Å resolution cryo-EM structure of SynDLP oligomers reveals the presence of oligomeric stalk interfaces typical for eukaryotic dynamin-like proteins. The bundle signaling element domain shows distinct features, such as an intramolecular disulfide bridge that affects the GTPase activity, or an expanded intermolecular interface with the GTPase domain. In addition to typical GD-GD contacts, such atypical GTPase domain interfaces might be a GTPase activity regulating tool in oligomerized SynDLP. Furthermore, we show that SynDLP interacts with and intercalates into membranes containing negatively charged thylakoid membrane lipids independent of nucleotides. The structural characteristics of SynDLP oligomers suggest it to be the closest known bacterial ancestor of eukaryotic dynamin.
001006880 536__ $$0G:(DE-HGF)POF4-5352$$a5352 - Understanding the Functionality of Soft Matter and Biomolecular Systems (POF4-535)$$cPOF4-535$$fPOF IV$$x0
001006880 536__ $$0G:(DE-HGF)POF4-5241$$a5241 - Molecular Information Processing in Cellular Systems (POF4-524)$$cPOF4-524$$fPOF IV$$x1
001006880 588__ $$aDataset connected to CrossRef, Journals: juser.fz-juelich.de
001006880 7001_ $$0P:(DE-HGF)0$$aGewehr, Lucas$$b1
001006880 7001_ $$0P:(DE-HGF)0$$aJilly, Ruven$$b2
001006880 7001_ $$0P:(DE-HGF)0$$aFranz, Johannes$$b3
001006880 7001_ $$0P:(DE-HGF)0$$aZu, Whenju Eva$$b4
001006880 7001_ $$0P:(DE-HGF)0$$aWeidner, Tobias$$b5
001006880 7001_ $$0P:(DE-HGF)0$$aBonn, Mischa$$b6
001006880 7001_ $$0P:(DE-Juel1)173949$$aSachse, Carsten$$b7$$eCorresponding author$$ufzj
001006880 7001_ $$0P:(DE-HGF)0$$aSchneider, Dirk$$b8$$eCorresponding author
001006880 773__ $$0PERI:(DE-600)2553671-0$$a10.1038/s41467-023-37746-9$$gVol. 14, no. 1, p. 2156$$n1$$p2156$$tNature Communications$$v14$$x2041-1723$$y2023
001006880 8564_ $$uhttps://juser.fz-juelich.de/record/1006880/files/SynDLP%20-%20publish%20-%2020.4.2023.pdf$$yOpenAccess
001006880 909CO $$ooai:juser.fz-juelich.de:1006880$$popenaire$$pdriver$$pVDB$$popen_access$$pdnbdelivery
001006880 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)181012$$aForschungszentrum Jülich$$b0$$kFZJ
001006880 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)173949$$aForschungszentrum Jülich$$b7$$kFZJ
001006880 9131_ $$0G:(DE-HGF)POF4-535$$1G:(DE-HGF)POF4-530$$2G:(DE-HGF)POF4-500$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$9G:(DE-HGF)POF4-5352$$aDE-HGF$$bKey Technologies$$lMaterials Systems Engineering$$vMaterials Information Discovery$$x0
001006880 9131_ $$0G:(DE-HGF)POF4-524$$1G:(DE-HGF)POF4-520$$2G:(DE-HGF)POF4-500$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$9G:(DE-HGF)POF4-5241$$aDE-HGF$$bKey Technologies$$lNatural, Artificial and Cognitive Information Processing$$vMolecular and Cellular Information Processing$$x1
001006880 9141_ $$y2023
001006880 915__ $$0StatID:(DE-HGF)0160$$2StatID$$aDBCoverage$$bEssential Science Indicators$$d2022-11-11
001006880 915__ $$0StatID:(DE-HGF)1190$$2StatID$$aDBCoverage$$bBiological Abstracts$$d2022-11-11
001006880 915__ $$0LIC:(DE-HGF)CCBY4$$2HGFVOC$$aCreative Commons Attribution CC BY 4.0
001006880 915__ $$0StatID:(DE-HGF)0113$$2StatID$$aWoS$$bScience Citation Index Expanded$$d2022-11-11
001006880 915__ $$0StatID:(DE-HGF)0700$$2StatID$$aFees$$d2022-11-11
001006880 915__ $$0StatID:(DE-HGF)0510$$2StatID$$aOpenAccess
001006880 915__ $$0StatID:(DE-HGF)0561$$2StatID$$aArticle Processing Charges$$d2022-11-11
001006880 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bNAT COMMUN : 2022$$d2023-08-29
001006880 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS$$d2023-08-29
001006880 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline$$d2023-08-29
001006880 915__ $$0StatID:(DE-HGF)0320$$2StatID$$aDBCoverage$$bPubMed Central$$d2023-08-29
001006880 915__ $$0StatID:(DE-HGF)0501$$2StatID$$aDBCoverage$$bDOAJ Seal$$d2023-05-02T09:09:09Z
001006880 915__ $$0StatID:(DE-HGF)0500$$2StatID$$aDBCoverage$$bDOAJ$$d2023-05-02T09:09:09Z
001006880 915__ $$0StatID:(DE-HGF)0030$$2StatID$$aPeer Review$$bDOAJ : Peer review$$d2023-05-02T09:09:09Z
001006880 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List$$d2023-08-29
001006880 915__ $$0StatID:(DE-HGF)1050$$2StatID$$aDBCoverage$$bBIOSIS Previews$$d2023-08-29
001006880 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection$$d2023-08-29
001006880 915__ $$0StatID:(DE-HGF)1030$$2StatID$$aDBCoverage$$bCurrent Contents - Life Sciences$$d2023-08-29
001006880 915__ $$0StatID:(DE-HGF)1060$$2StatID$$aDBCoverage$$bCurrent Contents - Agriculture, Biology and Environmental Sciences$$d2023-08-29
001006880 915__ $$0StatID:(DE-HGF)1040$$2StatID$$aDBCoverage$$bZoological Record$$d2023-08-29
001006880 915__ $$0StatID:(DE-HGF)1150$$2StatID$$aDBCoverage$$bCurrent Contents - Physical, Chemical and Earth Sciences$$d2023-08-29
001006880 915__ $$0StatID:(DE-HGF)9915$$2StatID$$aIF >= 15$$bNAT COMMUN : 2022$$d2023-08-29
001006880 920__ $$lyes
001006880 9201_ $$0I:(DE-Juel1)ER-C-3-20170113$$kER-C-3$$lStrukturbiologie$$x0
001006880 980__ $$ajournal
001006880 980__ $$aVDB
001006880 980__ $$aI:(DE-Juel1)ER-C-3-20170113
001006880 980__ $$aUNRESTRICTED
001006880 9801_ $$aFullTexts