Contribution to a conference proceedings/Contribution to a book FZJ-2023-01988

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Uncertainty-Aware Contour Proposal Networks for Cell Segmentation in Multi-Modality High-Resolution Microscopy Images

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2022

Proceedings of the NeurIPS CellSeg 2022 Challenge
NeurIPS 2022 Weakly Supervised Cell Segmentation in Multi-modality High-Resolution Microscopy Images, NeurIPS CellSeg 2022, New OrleansNew Orleans, USA, 6 Dec 2022 - 6 Dec 20222022-12-062022-12-06
12 pp. ()

Abstract: We present a simple framework for cell segmentation, based on uncertainty-aware Contour Proposal Networks (CPNs). It is designed to provide high segmentation accuracy while remaining computationally efficient, which makes it an ideal solution for high throughput microscopy applications. Each predicted cell is provided with four uncertainty estimations that give information about the localization accuracy of the detected cell boundaries. Such additional insights are valuable for downstream single-cell analysis in microscopy image-based biology and biomedical research. In the context of the NeurIPS 22 Cell Segmentation Challenge, the proposed solution is shown to generalize well in a multi-modality setting, while respecting domain-specific requirements such as focusing on specific cell types. Without an ensemble or test-time augmentation the method achieves an F1 score of 0.8986 on the challenge's validation set.Code is available at https://github.com/FZJ-INM1-BDA/neurips22-cell-seg.


Contributing Institute(s):
  1. Strukturelle und funktionelle Organisation des Gehirns (INM-1)
Research Program(s):
  1. 5254 - Neuroscientific Data Analytics and AI (POF4-525) (POF4-525)
  2. HBP SGA3 - Human Brain Project Specific Grant Agreement 3 (945539) (945539)
  3. HIBALL - Helmholtz International BigBrain Analytics and Learning Laboratory (HIBALL) (InterLabs-0015) (InterLabs-0015)
  4. DFG project 313856816 - SPP 2041: Computational Connectomics (313856816) (313856816)
  5. Helmholtz AI - Helmholtz Artificial Intelligence Coordination Unit – Local Unit FZJ (E.40401.62) (E.40401.62)

Appears in the scientific report 2023
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 Record created 2023-05-05, last modified 2024-02-26



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