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@ARTICLE{MoralesGregorio:1007691,
author = {Morales-Gregorio, Aitor and van Meegen, Alexander and van
Albada, Sacha J},
title = {{U}biquitous lognormal distribution of neuron densities in
mammalian cerebral cortex},
journal = {Cerebral cortex},
volume = {33},
number = {16},
issn = {1047-3211},
address = {Oxford},
publisher = {Oxford Univ. Press},
reportid = {FZJ-2023-02165},
pages = {9439-9449},
year = {2023},
abstract = {Numbers of neurons and their spatial variation are
fundamental organizational features of the brain. Despite
the large corpus of cytoarchitectonic data available in the
literature, the statistical distributions of neuron
densities within and across brain areas remain largely
uncharacterized. Here, we show that neuron densities are
compatible with a lognormal distribution across cortical
areas in several mammalian species, and find that this also
holds true within cortical areas. A minimal model of noisy
cell division, in combination with distributed proliferation
times, can account for the coexistence of lognormal
distributions within and across cortical areas. Our findings
uncover a new organizational principle of cortical
cytoarchitecture: the ubiquitous lognormal distribution of
neuron densities, which adds to a long list of lognormal
variables in the brain.},
cin = {INM-6 / IAS-6 / INM-10},
ddc = {610},
cid = {I:(DE-Juel1)INM-6-20090406 / I:(DE-Juel1)IAS-6-20130828 /
I:(DE-Juel1)INM-10-20170113},
pnm = {5231 - Neuroscientific Foundations (POF4-523) / HBP SGA3 -
Human Brain Project Specific Grant Agreement 3 (945539) /
DFG project 347572269 - Heterogenität von Zytoarchitektur,
Chemoarchitektur und Konnektivität in einem großskaligen
Computermodell der menschlichen Großhirnrinde (347572269) /
HBP SGA2 - Human Brain Project Specific Grant Agreement 2
(785907)},
pid = {G:(DE-HGF)POF4-5231 / G:(EU-Grant)945539 /
G:(GEPRIS)347572269 / G:(EU-Grant)785907},
typ = {PUB:(DE-HGF)16},
pubmed = {37409647},
UT = {WOS:001022939900001},
doi = {10.1093/cercor/bhad160},
url = {https://juser.fz-juelich.de/record/1007691},
}