TY  - JOUR
AU  - Thies, Tabea
AU  - Mücke, Doris
AU  - Geerts, Nuria
AU  - Seger, Aline
AU  - Fink, Gereon Rudolf
AU  - Barbe, Michael
AU  - Sommerauer, Michael
TI  - Compensatory articulatory mechanisms preserve intelligibility in prodromal Parkinson's disease
JO  - Parkinsonism & related disorders
VL  - 112
SN  - 1353-8020
CY  - Amsterdam [u.a.]
PB  - Elsevier Science
M1  - FZJ-2023-02379
SP  - 105487 -
PY  - 2023
AB  - AbstractIntroduction: Dysarthria is highly prevalent in patients with Parkinson's disease (PD) and speech changes have already been detected in patients with prodromal PD on the acoustic level. However, the present study directly tracks underlying articulatory movements with electromagnetic articulography to investigate early speech alterations on the kinematic level in isolated REM sleep behavior disorder (iRBD) and compares them to PD and control speakers.Methods: Kinematic data of 23 control speakers, 22 speakers with iRBD, and 23 speakers with PD were collected. Amplitude, duration, and average speed of lower lip, tongue tip, and tongue body movements were analyzed. Naive listeners rated the intelligibility of all speakers.Results: Patients with iRBD produced tongue tip and tongue body movements that were larger in amplitude and longer in duration compared to control speakers, while remaining intelligible. Compared to patients with iRBD, patients with PD had smaller, longer and slower tongue tip and lower lip movements, accompanied by lower intelligibility. Thus, the data indicate that the lingual system is already affected in prodromal PD. Furthermore, lower lip and especially tongue tip movements slow down and speech intelligibility decreases if motor impairment is more pronounced.Conclusion: Patients with iRBD adjust articulatory patterns to counteract incipient motor detriment on speech to maintain their intelligibility level.
LB  - PUB:(DE-HGF)16
C6  - 37329726
UR  - <Go to ISI:>//WOS:001024691600001
DO  - DOI:10.1016/j.parkreldis.2023.105487
UR  - https://juser.fz-juelich.de/record/1008542
ER  -