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@ARTICLE{Li:1008666,
author = {Li, Xuan and Friedrich, Patrick and Patil, Kaustubh R. and
Eickhoff, Simon B. and Weis, Susanne},
title = {{A} topography-based predictive framework for naturalistic
viewing f{MRI}},
journal = {NeuroImage},
volume = {277},
number = {.},
issn = {1053-8119},
address = {Orlando, Fla.},
publisher = {Academic Press},
reportid = {FZJ-2023-02466},
pages = {120245 -},
year = {2023},
note = {This work was supported by the European Union's Horizon
2020 Research and Innovation Programme under grant agreement
no. 945539 (HBP SGA3), and the Deutsche
Forschungsgemeinschaft (491111487).},
abstract = {Functional magnetic resonance imaging (fMRI) during
naturalistic viewing (NV) provides exciting opportunities
for studying brain functions in more ecologically valid
settings. Understanding individual differences in brain
functions during NV and their behavioural relevance has
recently become an important goal. However, methods
specifically designed for this purpose remain limited. Here,
we propose a topography-based predictive framework (TOPF) to
fill this methodological gap. TOPF identifies
individual-specific evoked activity topographies in a
data-driven manner and examines their behavioural relevance
using a machine learning-based predictive framework. We
validate TOPF on both NV and task-based fMRI data from
multiple conditions. Our results show that TOPF effectively
and stably captures individual differences in evoked brain
activity and successfully predicts phenotypes across
cognition, emotion and personality on unseen subjects from
their activity topographies. Moreover, TOPF compares
favourably with functional connectivity-based approaches in
prediction performance, with the identified predictive brain
regions being neurobiologically interpretable. Crucially, we
highlight the importance of examining individual evoked
brain activity topographies in advancing our understanding
of the brain-behaviour relationship. We believe that the
TOPF approach provides a simple but powerful tool for
understanding brain-behaviour relationships on an individual
level with a strong potential for clinical applications.},
cin = {INM-7},
ddc = {610},
cid = {I:(DE-Juel1)INM-7-20090406},
pnm = {5251 - Multilevel Brain Organization and Variability
(POF4-525) / HBP SGA3 - Human Brain Project Specific Grant
Agreement 3 (945539)},
pid = {G:(DE-HGF)POF4-5251 / G:(EU-Grant)945539},
typ = {PUB:(DE-HGF)16},
pubmed = {37353099},
UT = {WOS:001038690500001},
doi = {10.1016/j.neuroimage.2023.120245},
url = {https://juser.fz-juelich.de/record/1008666},
}