001008827 001__ 1008827
001008827 005__ 20250701125904.0
001008827 0247_ $$2doi$$a10.18154/RWTH-2023-02240
001008827 0247_ $$2datacite_doi$$a10.34734/FZJ-2023-02499
001008827 037__ $$aFZJ-2023-02499
001008827 041__ $$aGerman
001008827 1001_ $$0P:(DE-Juel1)180572$$aDimroth, Anton$$b0$$eCorresponding author$$ufzj
001008827 245__ $$aAuslegung einer Lager- und Antriebseinheit für ein neuartiges Röntgentarget zur Strahlentherapie$$f - 2023-02-15
001008827 260__ $$bRWTH Aachen University$$c2023
001008827 300__ $$apages Online-Ressource |b Illustrationen, Diagramme
001008827 3367_ $$2DataCite$$aOutput Types/Dissertation
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001008827 3367_ $$0PUB:(DE-HGF)11$$2PUB:(DE-HGF)$$aDissertation / PhD Thesis$$bphd$$mphd$$s1688461002_17922
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001008827 502__ $$aDissertation, RWTH Aachen, 2023$$bDissertation$$cRWTH Aachen$$d2023
001008827 520__ $$aCancer is one of the major health problems in Europe and leads to enormous socioeconomic burdens. In 2019, 1.55 million people in the EU died from cancer, and 50\% of all cancer patients receive radiotherapy during the course of their disease. Microbeam radiation therapy is a promising approach to successfully minimize the damage to healthy tissue. Preclinical research with MST only became possible with the advent of large synchrotron facilities in the 1990s. However, these costly research facilities are unsuitable for widespread use in the healthcare system, leaving an unmet need for compact sources of microbeam therapy. The core of this work is the design and construction of a bearing and drive unit of a novel x-ray target for a compact microbeam source prototype. In addition to the historical development of x-ray sources, a principal design system is described in which the three bearing variants: rolling bearings, magnetic bearings and sliding bearings are compared on the basis of their technical characteristrics. The principle of a liquid metal lubricated plain bearing provided the best compromise with respect to the given requirements. For the design of the bearing system, the state of the art is analyzed based on a literature review. The relevant fundamentals for modeling the bearing, taking turbulence and cavitation into account, are presented. A recalculation and comparison with other models from the literature is carried out using numerical methods and an analytical solution of the pressure distribution. Based on this, the optimized parameters for the bearing of the rotating anode are calculated. In addition, the influences of frictional heat, manufacturing aspects of the bearing and corrosion due to the liquid metal are discussed and preventive measures are taken. With the bearing calculation completed, the design, construction and calculation of the drive train with target connection is carried out, which consists of two rotating rotor carriers running concentrically around a stationary axis. The liquid metal bearing is formed between the axis and the rotating anode. An asynchronous machine with a separation tube as vacuum boundary drives the rotor. As part of a preliminary test, the behaviour of the liquid metal when it is filled into a vacuum chamber is investigated. For the overall system integration, which consists of a total of 4635 individual parts, the construction and assembly within a radiation protection cabinet is considered and the boundary conditions are planned and carried out.
001008827 536__ $$0G:(DE-HGF)POF4-899$$a899 - ohne Topic (POF4-899)$$cPOF4-899$$fPOF IV$$x0
001008827 536__ $$0G:(GEPRIS)416790481$$aDFG project 416790481 - Tumortherapie mit Mikrostrahlen an kompakter Strahlenquelle (416790481)$$c416790481$$x1
001008827 588__ $$aDataset connected to DataCite
001008827 650_7 $$2Other$$amicrobeam radiotherapy , spiral groove bearing , liquid metal bearing , X-ray
001008827 7001_ $$0P:(DE-Juel1)142196$$aNatour, Ghaleb$$b1$$eThesis advisor
001008827 7001_ $$0P:(DE-Juel1)129795$$aSingheiser, Lorenz$$b2$$eThesis advisor$$ufzj
001008827 7001_ $$0P:(DE-HGF)0$$aKowalski, Julia$$b3$$eThesis advisor
001008827 773__ $$a10.18154/RWTH-2023-02240
001008827 8564_ $$uhttps://juser.fz-juelich.de/record/1008827/files/952790.pdf$$yOpenAccess
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001008827 9141_ $$y2023
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001008827 981__ $$aI:(DE-Juel1)ITE-20250108