001     1008827
005     20250701125904.0
024 7 _ |a 10.18154/RWTH-2023-02240
|2 doi
024 7 _ |a 10.34734/FZJ-2023-02499
|2 datacite_doi
037 _ _ |a FZJ-2023-02499
041 _ _ |a German
100 1 _ |a Dimroth, Anton
|0 P:(DE-Juel1)180572
|b 0
|e Corresponding author
|u fzj
245 _ _ |a Auslegung einer Lager- und Antriebseinheit für ein neuartiges Röntgentarget zur Strahlentherapie
|f - 2023-02-15
260 _ _ |c 2023
|b RWTH Aachen University
300 _ _ |a pages Online-Ressource |b Illustrationen, Diagramme
336 7 _ |a Output Types/Dissertation
|2 DataCite
336 7 _ |a DISSERTATION
|2 ORCID
336 7 _ |a PHDTHESIS
|2 BibTeX
336 7 _ |a Thesis
|0 2
|2 EndNote
336 7 _ |a Dissertation / PhD Thesis
|b phd
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|s 1688461002_17922
|2 PUB:(DE-HGF)
336 7 _ |a doctoralThesis
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502 _ _ |a Dissertation, RWTH Aachen, 2023
|c RWTH Aachen
|b Dissertation
|d 2023
520 _ _ |a Cancer is one of the major health problems in Europe and leads to enormous socioeconomic burdens. In 2019, 1.55 million people in the EU died from cancer, and 50\% of all cancer patients receive radiotherapy during the course of their disease. Microbeam radiation therapy is a promising approach to successfully minimize the damage to healthy tissue. Preclinical research with MST only became possible with the advent of large synchrotron facilities in the 1990s. However, these costly research facilities are unsuitable for widespread use in the healthcare system, leaving an unmet need for compact sources of microbeam therapy. The core of this work is the design and construction of a bearing and drive unit of a novel x-ray target for a compact microbeam source prototype. In addition to the historical development of x-ray sources, a principal design system is described in which the three bearing variants: rolling bearings, magnetic bearings and sliding bearings are compared on the basis of their technical characteristrics. The principle of a liquid metal lubricated plain bearing provided the best compromise with respect to the given requirements. For the design of the bearing system, the state of the art is analyzed based on a literature review. The relevant fundamentals for modeling the bearing, taking turbulence and cavitation into account, are presented. A recalculation and comparison with other models from the literature is carried out using numerical methods and an analytical solution of the pressure distribution. Based on this, the optimized parameters for the bearing of the rotating anode are calculated. In addition, the influences of frictional heat, manufacturing aspects of the bearing and corrosion due to the liquid metal are discussed and preventive measures are taken. With the bearing calculation completed, the design, construction and calculation of the drive train with target connection is carried out, which consists of two rotating rotor carriers running concentrically around a stationary axis. The liquid metal bearing is formed between the axis and the rotating anode. An asynchronous machine with a separation tube as vacuum boundary drives the rotor. As part of a preliminary test, the behaviour of the liquid metal when it is filled into a vacuum chamber is investigated. For the overall system integration, which consists of a total of 4635 individual parts, the construction and assembly within a radiation protection cabinet is considered and the boundary conditions are planned and carried out.
536 _ _ |a 899 - ohne Topic (POF4-899)
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536 _ _ |a DFG project 416790481 - Tumortherapie mit Mikrostrahlen an kompakter Strahlenquelle (416790481)
|0 G:(GEPRIS)416790481
|c 416790481
|x 1
588 _ _ |a Dataset connected to DataCite
650 _ 7 |a microbeam radiotherapy , spiral groove bearing , liquid metal bearing , X-ray
|2 Other
700 1 _ |a Natour, Ghaleb
|0 P:(DE-Juel1)142196
|b 1
|e Thesis advisor
700 1 _ |a Singheiser, Lorenz
|0 P:(DE-Juel1)129795
|b 2
|e Thesis advisor
|u fzj
700 1 _ |a Kowalski, Julia
|0 P:(DE-HGF)0
|b 3
|e Thesis advisor
773 _ _ |a 10.18154/RWTH-2023-02240
856 4 _ |u https://juser.fz-juelich.de/record/1008827/files/952790.pdf
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909 C O |o oai:juser.fz-juelich.de:1008827
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910 1 _ |a Forschungszentrum Jülich
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910 1 _ |a Forschungszentrum Jülich
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910 1 _ |a Forschungszentrum Jülich
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913 1 _ |a DE-HGF
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914 1 _ |y 2023
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981 _ _ |a I:(DE-Juel1)ITE-20250108


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