001009076 001__ 1009076
001009076 005__ 20240313094854.0
001009076 037__ $$aFZJ-2023-02624
001009076 041__ $$aEnglish
001009076 1001_ $$0P:(DE-Juel1)190767$$aShimoura, Renan$$b0$$eCorresponding author$$ufzj
001009076 1112_ $$aNEST Conference 2023$$cvirtual$$d2023-06-15 - 2023-06-16$$wvirtual
001009076 245__ $$aVisual alpha generators in a full-density spiking thalamocortical model
001009076 260__ $$c2023
001009076 3367_ $$033$$2EndNote$$aConference Paper
001009076 3367_ $$2DataCite$$aOther
001009076 3367_ $$2BibTeX$$aINPROCEEDINGS
001009076 3367_ $$2DRIVER$$aconferenceObject
001009076 3367_ $$2ORCID$$aLECTURE_SPEECH
001009076 3367_ $$0PUB:(DE-HGF)6$$2PUB:(DE-HGF)$$aConference Presentation$$bconf$$mconf$$s1689926001_19807$$xOther
001009076 520__ $$aThe alpha rhythm (~10 Hz) is a prominent feature in the electroencephalograms of various mammals and is associated with reduced visual attention and with functions such as timing regulation and transmission facilitation [1]. Although the exact mechanism of alpha rhythm generation is still unclear, the thalamus and cortex have been proposed as possible protagonists. In this study, a full-density spiking thalamocortical model of neural circuits in the primary visual cortex and the lateral geniculate nucleus was built using the NEST simulator, to investigate two potential alpha rhythm generators. The first mechanism involves rhythmic bursts produced by pyramidal neurons in layer 5 at around 10 Hz [2], while the second mechanism relies on a thalamocortical loop delay of approximately 100 ms [3]. The model comprises excitatory and inhibitory populations of adaptive exponential integrate-and-fire model neurons. The resulting spiking activity was recorded and compared with experimental data using power spectra and Granger causality analysis. The results indicate that both mechanisms can generate and spread alpha oscillations but with different laminar patterns. The first mechanism suggests that the alpha rhythm mainly originates in layers 5 and 2/3 (similar as in [4]), while the second mechanism points to layers 4 and 6 (similar as in [5]). Combining both mechanisms results in a summation of effects, with the alpha range emanating from all layers. The findings suggest that the two mechanisms may contribute differently to alpha rhythms, with distinct laminar patterns, and may be expressed either separately or in tandem under different conditions.
001009076 536__ $$0G:(DE-HGF)POF4-5231$$a5231 - Neuroscientific Foundations (POF4-523)$$cPOF4-523$$fPOF IV$$x0
001009076 536__ $$0G:(EU-Grant)785907$$aHBP SGA2 - Human Brain Project Specific Grant Agreement 2 (785907)$$c785907$$fH2020-SGA-FETFLAG-HBP-2017$$x1
001009076 536__ $$0G:(EU-Grant)945539$$aHBP SGA3 - Human Brain Project Specific Grant Agreement 3 (945539)$$c945539$$fH2020-SGA-FETFLAG-HBP-2019$$x2
001009076 536__ $$0G:(GEPRIS)347572269$$aDFG project 347572269 - Heterogenität von Zytoarchitektur, Chemoarchitektur und Konnektivität in einem großskaligen Computermodell der menschlichen Großhirnrinde (347572269)$$c347572269$$x3
001009076 7001_ $$0P:(DE-HGF)0$$aRoque, Antonio Carlos$$b1
001009076 7001_ $$0P:(DE-Juel1)138512$$avan Albada, Sacha$$b2$$ufzj
001009076 909CO $$ooai:juser.fz-juelich.de:1009076$$pec_fundedresources$$pVDB$$popenaire
001009076 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)190767$$aForschungszentrum Jülich$$b0$$kFZJ
001009076 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)138512$$aForschungszentrum Jülich$$b2$$kFZJ
001009076 9131_ $$0G:(DE-HGF)POF4-523$$1G:(DE-HGF)POF4-520$$2G:(DE-HGF)POF4-500$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$9G:(DE-HGF)POF4-5231$$aDE-HGF$$bKey Technologies$$lNatural, Artificial and Cognitive Information Processing$$vNeuromorphic Computing and Network Dynamics$$x0
001009076 9141_ $$y2023
001009076 9201_ $$0I:(DE-Juel1)INM-6-20090406$$kINM-6$$lComputational and Systems Neuroscience$$x0
001009076 9201_ $$0I:(DE-Juel1)IAS-6-20130828$$kIAS-6$$lTheoretical Neuroscience$$x1
001009076 9201_ $$0I:(DE-Juel1)INM-10-20170113$$kINM-10$$lJara-Institut Brain structure-function relationships$$x2
001009076 980__ $$aconf
001009076 980__ $$aVDB
001009076 980__ $$aI:(DE-Juel1)INM-6-20090406
001009076 980__ $$aI:(DE-Juel1)IAS-6-20130828
001009076 980__ $$aI:(DE-Juel1)INM-10-20170113
001009076 980__ $$aUNRESTRICTED
001009076 981__ $$aI:(DE-Juel1)IAS-6-20130828