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@ARTICLE{Miranda:1009717,
      author       = {Miranda, Alan and Kroll, Tina and Schweda, Vanessa and
                      Staelens, Steven G and Verhaeghe, Jeroen},
      title        = {{C}orrection of motion tracking errors for {PET} head rigid
                      motion correction},
      journal      = {Physics in medicine and biology},
      volume       = {68},
      issn         = {0031-9155},
      address      = {Bristol},
      publisher    = {IOP Publ.},
      reportid     = {FZJ-2023-02949},
      pages        = {175009},
      year         = {2023},
      abstract     = {In positron emission tomography (PET) rigid motion
                      correction, erroneous tracking information translates into
                      reduced quality in motion corrected reconstructions. We aim
                      to improve the accuracy of the motion tracking data, to
                      improve the quality of motion corrected reconstructions.We
                      developed a method for correction of marker/skin
                      displacement over the skull, for tracking methods which
                      require multiple markers attached on the subject head.
                      Additionally, we correct for small magnitude (~1 - 2 mm)
                      residual translation tracking errors that can still be
                      present after other corrections. We performed [18F]FDG scans
                      in awake mice (n = 8) and rats (n = 8), and dynamic
                      [18F]SynVesT-1 scans in awake mice (n = 8). Head tracking
                      was performed with the point source tracking method,
                      attaching 3 to 4 radioactive fiducial markers on the
                      animals' heads. List-mode even-by-event motion correction
                      reconstruction was performed using tracking data obtained
                      from the point source tracking method (MC), tracking data
                      corrected for marker displacement (MC-DC), and tracking data
                      with additional correction for residual translation tracking
                      errors (MC-DCT). Image contrast, and the image enhancement
                      metric (IEM, with MC as reference) were calculated in these
                      3 reconstructions.In mice [18F]FDG scans, the contrast
                      increased on average $3\%$ from MC to MC-DC (IEM: 1.01), and
                      $5\%$ from MC to MC-DCT (IEM: 1.02). For mice [18F]SynVesT-1
                      scans the contrast increased $6\%$ from MC to MC-DC (IEM:
                      1.03), and $7\%$ from MC to MC-DCT (IEM: 1.05). In rat
                      [18F]FDG scans contrast increased $5\%$ (IEM: 1.04), and
                      $9\%$ (IEM: 1.05), respectively.The methods presented here
                      serve to correct motion tracking errors in PET brain scans,
                      which translates into improved image quality in motion
                      corrected reconstructions.},
      cin          = {INM-2},
      ddc          = {530},
      cid          = {I:(DE-Juel1)INM-2-20090406},
      pnm          = {5253 - Neuroimaging (POF4-525)},
      pid          = {G:(DE-HGF)POF4-5253},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {37524092},
      UT           = {WOS:001049369900001},
      doi          = {10.1088/1361-6560/acec2c},
      url          = {https://juser.fz-juelich.de/record/1009717},
}