% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Bloch:1010194,
      author       = {Bloch, Carola and Viswanathan, Shivakumar and Tepest, Ralf
                      and Jording, Mathis and Falter-Wagner, Christine M. and
                      Vogeley, Kai},
      title        = {{D}ifferentiated, rather than shared, strategies for
                      time-coordinated action in social and non-social domains in
                      autistic individuals},
      journal      = {Cortex},
      volume       = {166},
      issn         = {0010-9452},
      address      = {New York, NY},
      publisher    = {Elsevier},
      reportid     = {FZJ-2023-03005},
      pages        = {207 - 232},
      year         = {2023},
      abstract     = {Autism spectrum disorder (ASD) is a neurodevelopmental
                      condition with a highly heterogeneous adult phenotype that
                      includes social and non-social behavioral characteristics.
                      The link between the characteristics assignable to the
                      different domains remains unresolved. One possibility is
                      that social and non-social behaviors in autism are modulated
                      by a common underlying deficit. However, here we report
                      evidence supporting an alternative concept that is
                      individual-centered rather than deficit-centered.
                      Individuals are assumed to have a distinctive style in the
                      strategies they adopt to perform social and non-social tasks
                      with these styles presumably being structured differently
                      between autistic individuals and typically-developed (TD)
                      individuals. We tested this hypothesis for the execution of
                      time-coordinated (synchronized) actions. Participants
                      performed (i) a social task that required synchronized gaze
                      and pointing actions to interact with another person, and
                      (ii) a non-social task that required finger-tapping actions
                      synchronized to periodic stimuli at different time-scales
                      and sensory modalities. In both tasks, synchronization
                      behavior differed between ASD and TD groups. However, a
                      principal component analysis of individual behaviors across
                      tasks revealed associations between social and non-social
                      features for the TD persons but such cross-domain
                      associations were strikingly absent for autistic
                      individuals. The highly differentiated strategies between
                      domains in ASD are inconsistent with a general
                      synchronization deficit and instead highlight the
                      individualized developmental heterogeneity in the
                      acquisition of domain-specific behaviors. We propose a
                      cognitive model to help disentangle individual-centered from
                      deficit-centered effects in other domains. Our findings
                      reinforce the importance to identify individually
                      differentiated phenotypes to personalize autism
                      therapies.Keywords: Adults; Autism; Cross-domain;
                      Neurodevelopmental conditions; Synchronization.},
      cin          = {INM-3},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-3-20090406},
      pnm          = {5251 - Multilevel Brain Organization and Variability
                      (POF4-525)},
      pid          = {G:(DE-HGF)POF4-5251},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {37393703},
      UT           = {WOS:001028749100001},
      doi          = {10.1016/j.cortex.2023.05.008},
      url          = {https://juser.fz-juelich.de/record/1010194},
}