% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Fan:1010488,
      author       = {Fan, Xiaoming and Tao, Lele and Zhou, Xiaoyu and He, Xiao
                      and Zhang, Yu and Huang, Haixin and Yang, Jiale and Wang,
                      Simei and Ma, Zhihui and Gensch, Thomas and Huang, Ruimin},
      title        = {{M}ethod for the refractive index of various tissues based
                      on fluorescence microscopy},
      journal      = {Optics continuum},
      volume       = {2},
      number       = {7},
      issn         = {2770-0208},
      address      = {Washington, DC},
      publisher    = {Optica Publishing Group},
      reportid     = {FZJ-2023-03083},
      pages        = {1638 -},
      year         = {2023},
      note         = {National Natural Science Foundation of China (82172001);
                      Instrument Function Development of ChineseAcademy of
                      Sciences; Natural Science Foundation of Shanghai
                      (21ZR1474800).},
      abstract     = {Refractive index is an important optical constant that
                      characterizes the interactionbetween light and specimen. A
                      difference in refractive index between specimen and
                      immersionmedium introduces the imaging aberration and leads
                      to a problem that the direct thicknessmeasurement of a
                      specimen by optical microscopy is not accurate. However,
                      this aberrationcorrection still requires the exact
                      information of the refractive index of specimen and
                      immersionmedium. Herein, we propose an imaging strategy to
                      estimate the refractive index for an unknownspecimen. A
                      simplified diffraction model is generated to obtain the
                      relationship between axialscaling factor and refractive
                      index. Then regular fluorescence microscopy is performed to
                      measurethe actual axial scaling factors of specimens from
                      mouse muscle and tumor xenograft. Referringto our
                      theoretical plot of axial scaling factor versus refractive
                      index, the refractive index of tissuespecimen is determined.
                      For example, we obtain a mean refractive index (n) value of
                      1.36 fornormal muscle tissues, and 1.41 for tumor
                      xenografts. We demonstrate that this diffractionmodel-based
                      estimation method is an alternative to the current
                      techniques, improving the accuratemeasurement for refractive
                      index of tissue specimen. The simple instrument requirement
                      with aneasy specimen preparation for this estimation method
                      of refractive index may increase the imagequality on tissue
                      specimens with less aberration.},
      cin          = {IBI-1},
      ddc          = {530},
      cid          = {I:(DE-Juel1)IBI-1-20200312},
      pnm          = {5244 - Information Processing in Neuronal Networks
                      (POF4-524)},
      pid          = {G:(DE-HGF)POF4-5244},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:001044896900010},
      doi          = {10.1364/OPTCON.492897},
      url          = {https://juser.fz-juelich.de/record/1010488},
}