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@ARTICLE{Leonide:10137,
      author       = {Leonide, A. and Rüger, B. and Weber, A. and Meulenberg, W.
                      A. and Ivers-Tiffée, E.},
      title        = {{I}mpedance {S}tudy of {A}lternative
                      ({L}a,{S}r){F}e{O}3-and ({L}a,{S}r)({C}o,{F}e){O}3- {MIEC}
                      {C}athode {C}ompositions},
      journal      = {Journal of the Electrochemical Society},
      volume       = {157},
      issn         = {0013-4651},
      address      = {Pennington, NJ},
      publisher    = {Electrochemical Society},
      reportid     = {PreJuSER-10137},
      pages        = {B234 - B239},
      year         = {2010},
      note         = {Funding by the Fuel Cell Research Alliance
                      Baden-Wurttemberg (project 23-729.90 5/371) is gratefully
                      acknowledged.},
      abstract     = {This open-label extension evaluated the long-term efficacy
                      and tolerability of rufinamide in patients with
                      Lennox-Gastaut syndrome (LGS) who had previously completed a
                      12-week double-blind study.In total, 124 patients (aged 4-37
                      years), receiving 1-3 concomitant antiepileptic drugs, were
                      treated with rufinamide approximately 25-60 mg/kg/day.
                      Efficacy was assessed by seizure frequency; tolerability by
                      adverse events (AEs) and laboratory tests.Overall, patients
                      were treated with rufinamide for a median (range) of 432
                      (10-1149) days. Reductions in seizure frequency were
                      observed throughout the study; during the last 12 months of
                      treatment, $41.0\%$ and $47.9\%$ of patients had > or =
                      $50\%$ reduction in total and tonic-atonic seizure
                      frequency, respectively. The most common AEs were vomiting
                      $(30.6\%)$ and pyrexia $(25.8\%).In$ this open-label
                      extension, rufinamide appeared to be an effective long-term
                      adjunctive therapy for the treatment of LGS-associated
                      seizures in children and young adults.},
      cin          = {IEF-1},
      ddc          = {540},
      cid          = {I:(DE-Juel1)VDB809},
      pnm          = {Rationelle Energieumwandlung},
      pid          = {G:(DE-Juel1)FUEK402},
      shelfmark    = {Electrochemistry / Materials Science, Coatings $\&$ Films},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000273222700026},
      doi          = {10.1149/1.3265473},
      url          = {https://juser.fz-juelich.de/record/10137},
}