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@ARTICLE{Hussain:1016721,
author = {Hussain, Mazhar and Qaim, Syed M. and Spahn, Ingo and
Aslam, M. Naveed and Neumaier, Bernd},
title = {{C}opper radionuclides for theranostic applications:
towards standardisation of their nuclear data. {A}
mini-review},
journal = {Frontiers in Chemistry},
volume = {11},
issn = {2296-2646},
address = {Lausanne},
publisher = {Frontiers Media},
reportid = {FZJ-2023-03713},
pages = {1270351},
year = {2023},
abstract = {Copper has several clinically relevant radioisotopes and
versatile coordination chemistry, allowing attachment of its
radionuclides to biological molecules. This characteristic
makes it suitable for applications in molecular imaging or
radionuclide targeted therapy. Of particular interest in
nuclear medicine today is the theranostic approach. This
brief review considers five radionuclides of copper. These
are Cu-60, Cu-61, Cu-62, Cu-64, and Cu-67. The first four
are positron emitters for imaging, and the last one Cu-67 is
a β--emitting radionuclide suitable for targeted therapy.
The emphasis here is on theory-aided evaluation of available
experimental data with a view to establishing standardised
cross-section database for production of the relevant
radionuclide in high purity. Evaluated cross section data of
the positron emitters have been already extensively
reported; so here they are only briefly reviewed. More
attention is given to the data of the 68Zn(p,2p)67Cu
intermediate energy reaction which is rather commonly used
for production of 67Cu.Keywords: nuclear model calculation;
nuclear reaction cross section; radionuclides of copper;
standardisation of nuclear data; theranostic approach; thick
target yield.},
cin = {INM-5},
ddc = {540},
cid = {I:(DE-Juel1)INM-5-20090406},
pnm = {5253 - Neuroimaging (POF4-525)},
pid = {G:(DE-HGF)POF4-5253},
typ = {PUB:(DE-HGF)16},
pubmed = {37841203},
UT = {WOS:001079579900001},
doi = {10.3389/fchem.2023.1270351},
url = {https://juser.fz-juelich.de/record/1016721},
}