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001017566 1001_ $$0P:(DE-HGF)0$$avon Gall, Charlotte$$b0$$eCorresponding author
001017566 245__ $$aChronotype-Dependent Sleep Loss Is Associated with a Lower Amplitude in Circadian Rhythm and a Higher Fragmentation of REM Sleep in Young Healthy Adults
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001017566 520__ $$aIn modern society, the time and duration of sleep on workdays are primarily determined by external factors, e.g., the alarm clock. This can lead to a misalignment of the intrinsically determined sleep timing, which is dependent on the individual chronotype, resulting in reduced sleep quality. Although this is highly relevant given the high incidence of sleep disorders, little is known about the effect of this misalignment on sleep architecture. Using Fitbit trackers and questionnaire surveys, our study aims to elucidate sleep timing, sleep architecture, and subjective sleep quality in young healthy adults (n = 59) under real-life conditions (average of 82.4 ± 9.7 days). Correlations between variables were calculated to identify the direction of relationships. On workdays, the midpoint of sleep was earlier, the sleep duration was shorter, and tiredness upon waking was higher than on free days. A higher discrepancy between sleep duration on workdays and free days was associated with a lower stability of the circadian rhythm of REM sleep and also with a higher fragmentation of REM sleep. Similarly, a higher tiredness upon waking on free days, thus under intrinsically determined sleep timing conditions, was associated with a lower proportion and a higher fragmentation of REM sleep. This suggests that the misalignment between extrinsically and intrinsically determined sleep timing affects the architecture of sleep stages, particularly REM sleep, which is closely connected to sleep quality.
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001017566 7001_ $$0P:(DE-HGF)0$$aHolub, Leon$$b1
001017566 7001_ $$0P:(DE-HGF)0$$aPfeffer, Martina$$b2
001017566 7001_ $$0P:(DE-Juel1)131678$$aEickhoff, Simon$$b3$$eCorresponding author
001017566 773__ $$0PERI:(DE-600)2651993-8$$a10.3390/brainsci13101482$$gVol. 13, no. 10, p. 1482 -$$n10$$p1482 -$$tBrain Sciences$$v13$$x2076-3425$$y2023
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