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@ARTICLE{vonGall:1017566,
      author       = {von Gall, Charlotte and Holub, Leon and Pfeffer, Martina
                      and Eickhoff, Simon},
      title        = {{C}hronotype-{D}ependent {S}leep {L}oss {I}s {A}ssociated
                      with a {L}ower {A}mplitude in {C}ircadian {R}hythm and a
                      {H}igher {F}ragmentation of {REM} {S}leep in {Y}oung
                      {H}ealthy {A}dults},
      journal      = {Brain Sciences},
      volume       = {13},
      number       = {10},
      issn         = {2076-3425},
      address      = {Basel},
      publisher    = {MDPI AG},
      reportid     = {FZJ-2023-04206},
      pages        = {1482 -},
      year         = {2023},
      abstract     = {In modern society, the time and duration of sleep on
                      workdays are primarily determined by external factors, e.g.,
                      the alarm clock. This can lead to a misalignment of the
                      intrinsically determined sleep timing, which is dependent on
                      the individual chronotype, resulting in reduced sleep
                      quality. Although this is highly relevant given the high
                      incidence of sleep disorders, little is known about the
                      effect of this misalignment on sleep architecture. Using
                      Fitbit trackers and questionnaire surveys, our study aims to
                      elucidate sleep timing, sleep architecture, and subjective
                      sleep quality in young healthy adults (n = 59) under
                      real-life conditions (average of 82.4 ± 9.7 days).
                      Correlations between variables were calculated to identify
                      the direction of relationships. On workdays, the midpoint of
                      sleep was earlier, the sleep duration was shorter, and
                      tiredness upon waking was higher than on free days. A higher
                      discrepancy between sleep duration on workdays and free days
                      was associated with a lower stability of the circadian
                      rhythm of REM sleep and also with a higher fragmentation of
                      REM sleep. Similarly, a higher tiredness upon waking on free
                      days, thus under intrinsically determined sleep timing
                      conditions, was associated with a lower proportion and a
                      higher fragmentation of REM sleep. This suggests that the
                      misalignment between extrinsically and intrinsically
                      determined sleep timing affects the architecture of sleep
                      stages, particularly REM sleep, which is closely connected
                      to sleep quality.},
      cin          = {INM-7},
      ddc          = {570},
      cid          = {I:(DE-Juel1)INM-7-20090406},
      pnm          = {5252 - Brain Dysfunction and Plasticity (POF4-525) / 5253 -
                      Neuroimaging (POF4-525)},
      pid          = {G:(DE-HGF)POF4-5252 / G:(DE-HGF)POF4-5253},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {37891848},
      UT           = {WOS:001094043700001},
      doi          = {10.3390/brainsci13101482},
      url          = {https://juser.fz-juelich.de/record/1017566},
}