%0 Journal Article
%A Lotter, Leon D.
%A Kohl, Simon H.
%A Gerloff, Christian
%A Bell, Laura
%A Niephaus, Alexandra
%A Kruppa, Jana A.
%A Dukart, Juergen
%A Schulte-Rüther, Martin
%A Reindl, Vanessa
%A Konrad, Kerstin
%T Revealing the neurobiology underlying interpersonal neural synchronization with multimodal data fusion
%J Neuroscience & biobehavioral reviews
%V 146
%@ 0149-7634
%C Amsterdam [u.a.]
%I Elsevier Science
%M FZJ-2023-04910
%P 105042 -
%D 2023
%Z Grant: DFG - CRC1451
%X Humans synchronize with one another to foster successful interactions. Here, we use a multimodal data fusion approach with the aim of elucidating the neurobiological mechanisms by which interpersonal neural synchronization (INS) occurs. Our meta-analysis of 22 functional magnetic resonance imaging and 69 near-infrared spectroscopy hyperscanning experiments (740 and 3721 subjects) revealed robust brain regional correlates of INS in the right temporoparietal junction and left ventral prefrontal cortex. Integrating this meta-analytic information with public databases, biobehavioral and brain-functional association analyses suggested that INS involves sensory-integrative hubs with functional connections to mentalizing and attention networks. On the molecular and genetic levels, we found INS to be associated with GABAergic neurotransmission and layer IV/V neuronal circuits, protracted developmental gene expression patterns, and disorders of neurodevelopment. Although limited by the indirect nature of phenotypic-molecular association analyses, our findings generate new testable hypotheses on the neurobiological basis of INS.
%F PUB:(DE-HGF)16
%9 Journal Article
%$ 36641012
%U <Go to ISI:>//WOS:000923809300001
%R 10.1016/j.neubiorev.2023.105042
%U https://juser.fz-juelich.de/record/1018582