TY  - JOUR
AU  - Lotter, Leon D.
AU  - Kohl, Simon H.
AU  - Gerloff, Christian
AU  - Bell, Laura
AU  - Niephaus, Alexandra
AU  - Kruppa, Jana A.
AU  - Dukart, Juergen
AU  - Schulte-Rüther, Martin
AU  - Reindl, Vanessa
AU  - Konrad, Kerstin
TI  - Revealing the neurobiology underlying interpersonal neural synchronization with multimodal data fusion
JO  - Neuroscience & biobehavioral reviews
VL  - 146
SN  - 0149-7634
CY  - Amsterdam [u.a.]
PB  - Elsevier Science
M1  - FZJ-2023-04910
SP  - 105042 -
PY  - 2023
N1  - Grant: DFG - CRC1451
AB  - Humans synchronize with one another to foster successful interactions. Here, we use a multimodal data fusion approach with the aim of elucidating the neurobiological mechanisms by which interpersonal neural synchronization (INS) occurs. Our meta-analysis of 22 functional magnetic resonance imaging and 69 near-infrared spectroscopy hyperscanning experiments (740 and 3721 subjects) revealed robust brain regional correlates of INS in the right temporoparietal junction and left ventral prefrontal cortex. Integrating this meta-analytic information with public databases, biobehavioral and brain-functional association analyses suggested that INS involves sensory-integrative hubs with functional connections to mentalizing and attention networks. On the molecular and genetic levels, we found INS to be associated with GABAergic neurotransmission and layer IV/V neuronal circuits, protracted developmental gene expression patterns, and disorders of neurodevelopment. Although limited by the indirect nature of phenotypic-molecular association analyses, our findings generate new testable hypotheses on the neurobiological basis of INS.
LB  - PUB:(DE-HGF)16
C6  - 36641012
UR  - <Go to ISI:>//WOS:000923809300001
DO  - DOI:10.1016/j.neubiorev.2023.105042
UR  - https://juser.fz-juelich.de/record/1018582
ER  -