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@ARTICLE{Lemke:1021443,
      author       = {Lemke, Moritz and Reiners, Jens and Smits, Sander H. J. and
                      Lakomek, Nils and Groth, Georg},
      title        = {{F}unctional reconstitution and structural characterization
                      of the plant hormone receptor {ETR}1 in lipid nanodiscs},
      journal      = {Chemical communications},
      volume       = {59},
      number       = {61},
      issn         = {0022-4936},
      address      = {Cambridge},
      publisher    = {Soc.},
      reportid     = {FZJ-2024-00739},
      pages        = {9344 - 9347},
      year         = {2023},
      abstract     = {The plant hormone receptor ETR1 regulates many highly
                      relevant agronomic processes. Today, significant functional
                      and structural questions remain unanswered regarding its
                      multi-pass transmembrane sensor domain able to bind and
                      respond to the gaseous plant hormone ethylene at femtomolar
                      concentrations. A significant reason for this is the lack of
                      structural data on full-length ETR1 in a lipid environment.
                      Herein, we present the functional reconstitution of
                      recombinant full-length ETR1 purified and solubilized from a
                      bacterial host into lipid nanodiscs, allowing the study of
                      the purified plant receptor for the first time in a
                      detergent-free membrane-like environment.},
      cin          = {IBI-7},
      ddc          = {540},
      cid          = {I:(DE-Juel1)IBI-7-20200312},
      pnm          = {5241 - Molecular Information Processing in Cellular Systems
                      (POF4-524) / DFG project 267205415 - SFB 1208: Identität
                      und Dynamik von Membransystemen - von Molekülen bis zu
                      zellulären Funktionen (267205415)},
      pid          = {G:(DE-HGF)POF4-5241 / G:(GEPRIS)267205415},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {37435887},
      UT           = {WOS:001027863000001},
      doi          = {10.1039/D3CC02619A},
      url          = {https://juser.fz-juelich.de/record/1021443},
}