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@ARTICLE{Gell:1022076,
author = {Gell, Martin and Langner, Robert and Küppers, Vincent and
Cieslik, Edna C. and Satterthwaite, Theodore D. and
Eickhoff, Simon B. and Müller, Veronika},
title = {{C}harting the brain networks of impulsivity:
{M}eta-analytic synthesis, functional connectivity modelling
and neurotransmitter associations},
reportid = {FZJ-2024-01213},
year = {2023},
abstract = {Impulsivity is a multidimensional construct that plays a
crucial role in human behaviour and is believed to be a
transdiagnostic marker of several psychiatric disorders.
However, given its multifaceted nature, comprehensive
investigations of its neural correlates are challenging. In
this study, we used a multi-modal approach to investigate
the functional network organisation of two domains in which
impulsivity manifests: decision-making and action control.
Within domain ALE meta-analyses identified two distinct
functional systems: one located in the default-mode network,
associated with value-based judgments and goal-directed
decision-making, and the other distributed across
higher-order networks associated with cognitive control.
These systems were organised into four specialised
communities of default-mode, cingulo-insular,
frontoparietal, and temporal regions. Integration within
those communities was associated with serotonin receptor
density. These findings reinforce insights from previous
behavioural research and provide substantial evidence for
the multidimensional nature of impulsivity on the neural
level.},
cin = {INM-7},
cid = {I:(DE-Juel1)INM-7-20090406},
pnm = {5251 - Multilevel Brain Organization and Variability
(POF4-525)},
pid = {G:(DE-HGF)POF4-5251},
typ = {PUB:(DE-HGF)25},
doi = {10.1101/2023.07.04.547631},
url = {https://juser.fz-juelich.de/record/1022076},
}