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@ARTICLE{Chu:1022517,
author = {Chu, Congying and Li, Wen and Shi, Weiyang and Wang, Haiyan
and Wang, Jiaojian and Liu, Yong and Liu, Bing and
Elmenhorst, David and Eickhoff, Simon B. and Fan, Lingzhong
and Jiang, Tianzi},
title = {{C}o-representation of functional brain networks is shaped
by cortical myeloarchitecture and reveals individual
behavioral ability},
journal = {The journal of neuroscience},
volume = {44},
number = {3},
issn = {0270-6474},
address = {Washington, DC},
publisher = {Soc.},
reportid = {FZJ-2024-01503},
pages = {e0856232024 -},
year = {2024},
abstract = {Large-scale functional networks are spatially distributed
in the human brain. Despite recent progress in
differentiating the functional roles of specific brain
networks, how the brain navigates the spatial coordination
among them and the biological relevance of this coordination
is still not fully understood. Capitalizing on canonical
individualized networks derived from functional MRI data, we
proposed a new concept, i.e., co-representation of
functional brain networks, to delineate the spatial
coordination among them. To further quantify the
co-representation pattern, we defined two indexes, i.e., the
co-representation specificity (CoRS) and intensity (CoRI),
for separately measuring the extent of specific and average
expression of functional networks at each brain location by
using the data from both sexes. We found that the identified
pattern of co-representation was anchored by cortical
regions with three types of cytoarchitectural classes along
a sensory-fugal axis, including, at the first end, primary
(idiotypic) regions showing high CoRS, at the second end,
heteromodal regions showing low CoRS and high CoRI, at the
third end, paralimbic regions showing low CoRI. Importantly,
we demonstrated the critical role of myeloarchitecture in
sculpting the spatial distribution of co-representation by
assessing the association with the myelin-related
neuroanatomical and transcriptomic profiles. Furthermore,
the significance of manifesting the co-representation was
revealed in its prediction of individual behavioral ability.
Our findings indicated that the spatial coordination among
functional networks was built upon an anatomically
configured blueprint to facilitate neural information
processing, while advancing our understanding of the
topographical organization of the brain by emphasizing the
assembly of functional networks.},
cin = {INM-7 / INM-2},
ddc = {610},
cid = {I:(DE-Juel1)INM-7-20090406 / I:(DE-Juel1)INM-2-20090406},
pnm = {5251 - Multilevel Brain Organization and Variability
(POF4-525) / 5252 - Brain Dysfunction and Plasticity
(POF4-525)},
pid = {G:(DE-HGF)POF4-5251 / G:(DE-HGF)POF4-5252},
typ = {PUB:(DE-HGF)16},
pubmed = {38290847},
UT = {WOS:001240724800007},
doi = {10.1523/JNEUROSCI.0856-23.2024},
url = {https://juser.fz-juelich.de/record/1022517},
}