001023460 001__ 1023460
001023460 005__ 20250204113806.0
001023460 0247_ $$2doi$$a10.1016/j.celrep.2024.113770
001023460 0247_ $$2ISSN$$a2211-1247
001023460 0247_ $$2ISSN$$a2639-1856
001023460 0247_ $$2datacite_doi$$a10.34734/FZJ-2024-01699
001023460 0247_ $$2pmid$$a38363683
001023460 0247_ $$2WOS$$aWOS:001188121400001
001023460 037__ $$aFZJ-2024-01699
001023460 082__ $$a610
001023460 1001_ $$aWang, Yaping$$b0
001023460 245__ $$aSpatio-molecular profiles shape the human cerebellar hierarchy along the sensorimotor-association axis
001023460 260__ $$a[New York, NY]$$bElsevier$$c2024
001023460 3367_ $$2DRIVER$$aarticle
001023460 3367_ $$2DataCite$$aOutput Types/Journal article
001023460 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1708525918_11605
001023460 3367_ $$2BibTeX$$aARTICLE
001023460 3367_ $$2ORCID$$aJOURNAL_ARTICLE
001023460 3367_ $$00$$2EndNote$$aJournal Article
001023460 520__ $$aCerebellar involvement in both motor and non-motor functions manifests in specific regions of the human cerebellum, revealing the functional heterogeneity within it. One compelling theory places the heterogeneity within the cerebellar functional hierarchy along the sensorimotor-association (SA) axis. Despite extensive neuroimaging studies, evidence for the cerebellar SA axis from different modalities and scales was lacking. Thus, we establish a significant link between the cerebellar SA axis and spatio-molecular profiles. Utilizing the gene set variation analysis, we find the intermediate biological principles the significant genes leveraged to scaffold the cerebellar SA axis. Interestingly, we find these spatio-molecular profiles notably associated with neuropsychiatric dysfunction and recent evolution. Furthermore, cerebello-cerebral interactions at genetic and functional connectivity levels mirror the cerebral cortex and cerebellum's SA axis. These findings can provide a deeper understanding of how the human cerebellar SA axis is shaped and its role in transitioning from sensorimotor to association functions.Keywords: CP: Neuroscience; brain evolution; functional hierarchy; gene expression; human cerebellum; neuropsychiatric disorder.
001023460 536__ $$0G:(DE-HGF)POF4-5251$$a5251 - Multilevel Brain Organization and Variability (POF4-525)$$cPOF4-525$$fPOF IV$$x0
001023460 588__ $$aDataset connected to CrossRef, Journals: juser.fz-juelich.de
001023460 7001_ $$aWang, Yufan$$b1
001023460 7001_ $$aWang, Haiyan$$b2
001023460 7001_ $$0P:(DE-HGF)0$$aMa, Liang$$b3
001023460 7001_ $$0P:(DE-Juel1)131678$$aEickhoff, Simon B.$$b4
001023460 7001_ $$aMadsen, Kristoffer Hougaard$$b5
001023460 7001_ $$aChu, Congying$$b6
001023460 7001_ $$00000-0002-4813-621X$$aFan, Lingzhong$$b7$$eCorresponding author
001023460 773__ $$0PERI:(DE-600)2649101-1$$a10.1016/j.celrep.2024.113770$$gVol. 43, no. 2, p. 113770 -$$n2$$p113770 -$$tCell reports$$v43$$x2211-1247$$y2024
001023460 8564_ $$uhttps://juser.fz-juelich.de/record/1023460/files/1-s2.0-S2211124724000986-main.pdf$$yOpenAccess
001023460 8564_ $$uhttps://juser.fz-juelich.de/record/1023460/files/1-s2.0-S2211124724000986-main.gif?subformat=icon$$xicon$$yOpenAccess
001023460 8564_ $$uhttps://juser.fz-juelich.de/record/1023460/files/1-s2.0-S2211124724000986-main.jpg?subformat=icon-180$$xicon-180$$yOpenAccess
001023460 8564_ $$uhttps://juser.fz-juelich.de/record/1023460/files/1-s2.0-S2211124724000986-main.jpg?subformat=icon-640$$xicon-640$$yOpenAccess
001023460 8564_ $$uhttps://juser.fz-juelich.de/record/1023460/files/1-s2.0-S2211124724000986-main.jpg?subformat=icon-1440$$xicon-1440$$yOpenAccess
001023460 909CO $$ooai:juser.fz-juelich.de:1023460$$pdnbdelivery$$pdriver$$pVDB$$popen_access$$popenaire
001023460 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)131678$$aForschungszentrum Jülich$$b4$$kFZJ
001023460 9131_ $$0G:(DE-HGF)POF4-525$$1G:(DE-HGF)POF4-520$$2G:(DE-HGF)POF4-500$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$9G:(DE-HGF)POF4-5251$$aDE-HGF$$bKey Technologies$$lNatural, Artificial and Cognitive Information Processing$$vDecoding Brain Organization and Dysfunction$$x0
001023460 9141_ $$y2024
001023460 915__ $$0StatID:(DE-HGF)0160$$2StatID$$aDBCoverage$$bEssential Science Indicators$$d2023-10-26
001023460 915__ $$0StatID:(DE-HGF)1190$$2StatID$$aDBCoverage$$bBiological Abstracts$$d2023-10-26
001023460 915__ $$0LIC:(DE-HGF)CCBYNCND4$$2HGFVOC$$aCreative Commons Attribution-NonCommercial-NoDerivs CC BY-NC-ND 4.0
001023460 915__ $$0StatID:(DE-HGF)0501$$2StatID$$aDBCoverage$$bDOAJ Seal$$d2023-05-02T08:49:39Z
001023460 915__ $$0StatID:(DE-HGF)0500$$2StatID$$aDBCoverage$$bDOAJ$$d2023-05-02T08:49:39Z
001023460 915__ $$0StatID:(DE-HGF)0113$$2StatID$$aWoS$$bScience Citation Index Expanded$$d2023-10-26
001023460 915__ $$0StatID:(DE-HGF)0700$$2StatID$$aFees$$d2023-10-26
001023460 915__ $$0StatID:(DE-HGF)0510$$2StatID$$aOpenAccess
001023460 915__ $$0StatID:(DE-HGF)0030$$2StatID$$aPeer Review$$bDOAJ : Anonymous peer review$$d2023-05-02T08:49:39Z
001023460 915__ $$0StatID:(DE-HGF)0561$$2StatID$$aArticle Processing Charges$$d2023-10-26
001023460 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS$$d2024-12-16
001023460 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bCELL REP : 2022$$d2024-12-16
001023460 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline$$d2024-12-16
001023460 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List$$d2024-12-16
001023460 915__ $$0StatID:(DE-HGF)1050$$2StatID$$aDBCoverage$$bBIOSIS Previews$$d2024-12-16
001023460 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection$$d2024-12-16
001023460 915__ $$0StatID:(DE-HGF)9905$$2StatID$$aIF >= 5$$bCELL REP : 2022$$d2024-12-16
001023460 920__ $$lyes
001023460 9201_ $$0I:(DE-Juel1)INM-7-20090406$$kINM-7$$lGehirn & Verhalten$$x0
001023460 980__ $$ajournal
001023460 980__ $$aVDB
001023460 980__ $$aUNRESTRICTED
001023460 980__ $$aI:(DE-Juel1)INM-7-20090406
001023460 9801_ $$aFullTexts