Home > Publications database > Analyzing Regional Organization of the Human Hippocampus in 3D-PLI Using Contrastive Learning and Geometric Unfolding > print

001     1023722
005     20240301205119.0
024 7 _ |a 10.48550/ARXIV.2402.17744
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037 _ _ |a FZJ-2024-01777
100 1 _ |a Oberstrass, Alexander
|0 P:(DE-HGF)0
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|e Corresponding author
245 _ _ |a Analyzing Regional Organization of the Human Hippocampus in 3D-PLI Using Contrastive Learning and Geometric Unfolding
260 _ _ |c 2024
|b arXiv
336 7 _ |a Preprint
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336 7 _ |a Electronic Article
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336 7 _ |a ARTICLE
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520 _ _ |a Understanding the cortical organization of the human brain requires interpretable descriptors for distinct structural and functional imaging data. 3D polarized light imaging (3D-PLI) is an imaging modality for visualizing fiber architecture in postmortem brains with high resolution that also captures the presence of cell bodies, for example, to identify hippocampal subfields. The rich texture in 3D-PLI images, however, makes this modality particularly difficult to analyze and best practices for characterizing architectonic patterns still need to be established. In this work, we demonstrate a novel method to analyze the regional organization of the human hippocampus in 3D-PLI by combining recent advances in unfolding methods with deep texture features obtained using a self-supervised contrastive learning approach. We identify clusters in the representations that correspond well with classical descriptions of hippocampal subfields, lending validity to the developed methodology.
536 _ _ |a 5254 - Neuroscientific Data Analytics and AI (POF4-525)
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536 _ _ |a HBP SGA3 - Human Brain Project Specific Grant Agreement 3 (945539)
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536 _ _ |a HIBALL - Helmholtz International BigBrain Analytics and Learning Laboratory (HIBALL) (InterLabs-0015)
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588 _ _ |a Dataset connected to DataCite
650 _ 7 |a Computer Vision and Pattern Recognition (cs.CV)
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650 _ 7 |a FOS: Computer and information sciences
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700 1 _ |a DeKraker, Jordan
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700 1 _ |a Palomero-Gallagher, Nicola
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700 1 _ |a Muenzing, Sascha E. A.
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700 1 _ |a Evans, Alan C.
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700 1 _ |a Axer, Markus
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700 1 _ |a Amunts, Katrin
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700 1 _ |a Dickscheid, Timo
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773 _ _ |a 10.48550/ARXIV.2402.17744
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|v Decoding Brain Organization and Dysfunction
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914 1 _ |y 2024
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