001024147 001__ 1024147 001024147 005__ 20250204113815.0 001024147 0247_ $$2doi$$a10.18416/IJMPI.2024.2403014 001024147 0247_ $$2datacite_doi$$a10.34734/FZJ-2024-01989 001024147 037__ $$aFZJ-2024-01989 001024147 041__ $$aEnglish 001024147 082__ $$a500 001024147 1001_ $$0P:(DE-Juel1)190282$$aBikulov, Timur$$b0$$eCorresponding author 001024147 1112_ $$aInternational Workshop on Magnetic Particle Imaging$$cFlüeli-Ranft$$d2024-03-13 - 2024-03-15$$gIWMPI 2024$$wSwitzerland 001024147 245__ $$aMulticontrasting MPS by dual-tone nonlinearity probing 001024147 260__ $$aLübeck$$bInfinite Science Publishing$$c2024 001024147 3367_ $$2DRIVER$$aarticle 001024147 3367_ $$0PUB:(DE-HGF)8$$2PUB:(DE-HGF)$$aContribution to a conference proceedings$$mcontrib 001024147 3367_ $$2DataCite$$aOutput Types/Journal article 001024147 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1712567327_21291 001024147 3367_ $$2BibTeX$$aARTICLE 001024147 3367_ $$2ORCID$$aJOURNAL_ARTICLE 001024147 3367_ $$00$$2EndNote$$aJournal Article 001024147 520__ $$aNovel MPI-based modalities such as multi-contrast imaging or remote viscosity recording require independent measurement of at least two or more magnetic particle types simultaneously. Particle response models based on the Fokker-Plank equation allow independent reconstruction of core and hydrodynamic diameters. However, due to complexity and stochastic character, they remain a black box for explaining the origin of measured nonlinear distortions. A model is required to suggest which frequency lines to measure, which fields to apply for reconstruction of particle core size distribution, and to explicitly show limitations of setup and measurement scheme (e.g., the range of core diameters available for reconstruction). Assuming that the amplitude of the sample magnetic moment and its distortions are determined by the number of excited magnetic moments, and response phase is governed by amplitude-dependent relaxation mechanisms, we show how and under what conditions two-tone systems become the key to independent measurement of the response from particles of different diameters. 001024147 536__ $$0G:(DE-HGF)POF4-5241$$a5241 - Molecular Information Processing in Cellular Systems (POF4-524)$$cPOF4-524$$fPOF IV$$x0 001024147 536__ $$0G:(GEPRIS)445454801$$aDFG project 445454801 - Kombinierter Feldeffekt-/Magnet-Immunsensor-Chip für den markierungsfreien Nachweise von Biomarkern (FEMIC) (445454801)$$c445454801$$x1 001024147 588__ $$aDataset connected to DataCite 001024147 650_7 $$2Other$$aMulti-contrast 001024147 650_7 $$2Other$$aFrequency mixing magnetic detection 001024147 650_7 $$2Other$$adual-frequency 001024147 650_7 $$2Other$$aDistribution Reconstruction 001024147 650_7 $$2Other$$aPassive Mixer Model 001024147 650_7 $$2Other$$aphase modulation 001024147 650_7 $$2Other$$ahydrodynamic size distribution 001024147 7001_ $$0P:(DE-Juel1)186710$$aEivazi, Faranak$$b1 001024147 7001_ $$0P:(DE-Juel1)128713$$aOffenhäusser, Andreas$$b2 001024147 7001_ $$0P:(DE-Juel1)128697$$aKrause, Hans-Joachim$$b3$$eCollaboration author 001024147 773__ $$0PERI:(DE-600)2893231-6$$a10.18416/IJMPI.2024.2403014$$n1$$p2403014$$tInternational journal on magnetic particle imaging$$v10$$x2365-9033$$y2024 001024147 8564_ $$uhttps://juser.fz-juelich.de/record/1024147/files/Published%20paper.pdf$$yOpenAccess 001024147 8564_ $$uhttps://juser.fz-juelich.de/record/1024147/files/Published%20paper.gif?subformat=icon$$xicon$$yOpenAccess 001024147 8564_ $$uhttps://juser.fz-juelich.de/record/1024147/files/Published%20paper.jpg?subformat=icon-1440$$xicon-1440$$yOpenAccess 001024147 8564_ $$uhttps://juser.fz-juelich.de/record/1024147/files/Published%20paper.jpg?subformat=icon-180$$xicon-180$$yOpenAccess 001024147 8564_ $$uhttps://juser.fz-juelich.de/record/1024147/files/Published%20paper.jpg?subformat=icon-640$$xicon-640$$yOpenAccess 001024147 909CO $$ooai:juser.fz-juelich.de:1024147$$pdnbdelivery$$pdriver$$pVDB$$popen_access$$popenaire 001024147 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)190282$$aForschungszentrum Jülich$$b0$$kFZJ 001024147 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)186710$$aForschungszentrum Jülich$$b1$$kFZJ 001024147 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)128713$$aForschungszentrum Jülich$$b2$$kFZJ 001024147 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)128697$$aForschungszentrum Jülich$$b3$$kFZJ 001024147 9131_ $$0G:(DE-HGF)POF4-524$$1G:(DE-HGF)POF4-520$$2G:(DE-HGF)POF4-500$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$9G:(DE-HGF)POF4-5241$$aDE-HGF$$bKey Technologies$$lNatural, Artificial and Cognitive Information Processing$$vMolecular and Cellular Information Processing$$x0 001024147 9141_ $$y2024 001024147 915__ $$0StatID:(DE-HGF)0510$$2StatID$$aOpenAccess 001024147 915__ $$0LIC:(DE-HGF)CCBY4$$2HGFVOC$$aCreative Commons Attribution CC BY 4.0 001024147 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS$$d2025-01-01 001024147 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline$$d2025-01-01 001024147 920__ $$lyes 001024147 9201_ $$0I:(DE-Juel1)IBI-3-20200312$$kIBI-3$$lBioelektronik$$x0 001024147 980__ $$ajournal 001024147 980__ $$aVDB 001024147 980__ $$aUNRESTRICTED 001024147 980__ $$acontrib 001024147 980__ $$aI:(DE-Juel1)IBI-3-20200312 001024147 9801_ $$aFullTexts