TY  - JOUR
AU  - Bikulov, Timur
AU  - Eivazi, Faranak
AU  - Offenhäusser, Andreas
TI  - Multicontrasting MPS by dual-tone nonlinearity probing
JO  - International journal on magnetic particle imaging
VL  - 10
IS  - 1
SN  - 2365-9033
CY  - Lübeck
PB  - Infinite Science Publishing
M1  - FZJ-2024-01989
SP  - 2403014
PY  - 2024
AB  - Novel MPI-based modalities such as multi-contrast imaging or remote viscosity recording require independent measurement of at least two or more magnetic particle types simultaneously. Particle response models based on the Fokker-Plank equation allow independent reconstruction of core and hydrodynamic diameters. However, due to complexity and stochastic character, they remain a black box for explaining the origin of measured nonlinear distortions. A model is required to suggest which frequency lines to measure, which fields to apply for reconstruction of particle core size distribution, and to explicitly show limitations of setup and measurement scheme (e.g., the range of core diameters available for reconstruction). Assuming that the amplitude of the sample magnetic moment and its distortions are determined by the number of excited magnetic moments, and response phase is governed by amplitude-dependent relaxation mechanisms, we show how and under what conditions two-tone systems become the key to independent measurement of the response from particles of different diameters.
T2  - International Workshop on Magnetic Particle Imaging
CY  - 13 Mar 2024 - 15 Mar 2024, Flüeli-Ranft (Switzerland)
Y2  - 13 Mar 2024 - 15 Mar 2024
M2  - Flüeli-Ranft, Switzerland
KW  - Multi-contrast (Other)
KW  - Frequency mixing magnetic detection (Other)
KW  - dual-frequency (Other)
KW  - Distribution Reconstruction (Other)
KW  - Passive Mixer Model (Other)
KW  - phase modulation (Other)
KW  - hydrodynamic size distribution (Other)
LB  - PUB:(DE-HGF)8 ; PUB:(DE-HGF)16
DO  - DOI:10.18416/IJMPI.2024.2403014
UR  - https://juser.fz-juelich.de/record/1024147
ER  -