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@ARTICLE{Bikulov:1024147,
      author       = {Bikulov, Timur and Eivazi, Faranak and Offenhäusser,
                      Andreas},
      collaboration = {Krause, Hans-Joachim},
      title        = {{M}ulticontrasting {MPS} by dual-tone nonlinearity probing},
      journal      = {International journal on magnetic particle imaging},
      volume       = {10},
      number       = {1},
      issn         = {2365-9033},
      address      = {Lübeck},
      publisher    = {Infinite Science Publishing},
      reportid     = {FZJ-2024-01989},
      pages        = {2403014},
      year         = {2024},
      abstract     = {Novel MPI-based modalities such as multi-contrast imaging
                      or remote viscosity recording require independent
                      measurement of at least two or more magnetic particle types
                      simultaneously. Particle response models based on the
                      Fokker-Plank equation allow independent reconstruction of
                      core and hydrodynamic diameters. However, due to complexity
                      and stochastic character, they remain a black box for
                      explaining the origin of measured nonlinear distortions. A
                      model is required to suggest which frequency lines to
                      measure, which fields to apply for reconstruction of
                      particle core size distribution, and to explicitly show
                      limitations of setup and measurement scheme (e.g., the range
                      of core diameters available for reconstruction). Assuming
                      that the amplitude of the sample magnetic moment and its
                      distortions are determined by the number of excited magnetic
                      moments, and response phase is governed by
                      amplitude-dependent relaxation mechanisms, we show how and
                      under what conditions two-tone systems become the key to
                      independent measurement of the response from particles of
                      different diameters.},
      month         = {Mar},
      date          = {2024-03-13},
      organization  = {International Workshop on Magnetic
                       Particle Imaging, Flüeli-Ranft
                       (Switzerland), 13 Mar 2024 - 15 Mar
                       2024},
      keywords     = {Multi-contrast (Other) / Frequency mixing magnetic
                      detection (Other) / dual-frequency (Other) / Distribution
                      Reconstruction (Other) / Passive Mixer Model (Other) / phase
                      modulation (Other) / hydrodynamic size distribution (Other)},
      cin          = {IBI-3},
      ddc          = {500},
      cid          = {I:(DE-Juel1)IBI-3-20200312},
      pnm          = {5241 - Molecular Information Processing in Cellular Systems
                      (POF4-524) / DFG project 445454801 - Kombinierter
                      Feldeffekt-/Magnet-Immunsensor-Chip für den
                      markierungsfreien Nachweise von Biomarkern (FEMIC)
                      (445454801)},
      pid          = {G:(DE-HGF)POF4-5241 / G:(GEPRIS)445454801},
      typ          = {PUB:(DE-HGF)8 / PUB:(DE-HGF)16},
      doi          = {10.18416/IJMPI.2024.2403014},
      url          = {https://juser.fz-juelich.de/record/1024147},
}