TY  - JOUR
AU  - Albert, Nathalie L
AU  - Galldiks, Norbert
AU  - Ellingson, Benjamin M
AU  - van den Bent, Martin J
AU  - Chang, Susan M
AU  - Cicone, Francesco
AU  - de Groot, John
AU  - Koh, Eng-Siew
AU  - Law, Ian
AU  - Le Rhun, Emilie
AU  - Mair, Maximilian J
AU  - Minniti, Giuseppe
AU  - Rudà, Roberta
AU  - Scott, Andrew M
AU  - Short, Susan C
AU  - Smits, Marion
AU  - Suchorska, Bogdana
AU  - Tolboom, Nelleke
AU  - Traub-Weidinger, Tatjana
AU  - Tonn, Joerg-Christian
AU  - Verger, Antoine
AU  - Weller, Michael
AU  - Wen, Patrick Y
AU  - Preusser, Matthias
TI  - PET-based response assessment criteria for diffuse gliomas (PET RANO 1.0): a report of the RANO group
JO  - The lancet / Oncology
VL  - 25
IS  - 1
SN  - 1470-2045
CY  - London
PB  - The Lancet Publ. Group
M1  - FZJ-2024-02268
SP  - e29 - e41
PY  - 2024
AB  - Response Assessment in Neuro-Oncology (RANO) response criteria have been established and were updated in 2023 for MRI-based response evaluation of diffuse gliomas in clinical trials. In addition, PET-based imaging with amino acid tracers is increasingly considered for disease monitoring in both clinical practice and clinical trials. So far, a standardised framework defining timepoints for baseline and follow-up investigations and response evaluation criteria for PET imaging of diffuse gliomas has not been established. Therefore, in this Policy Review, we propose a set of criteria for response assessment based on amino acid PET imaging in clinical trials enrolling participants with diffuse gliomas as defined in the 2021 WHO classification of tumours of the central nervous system. These proposed PET RANO criteria provide a conceptual framework that facilitates the structured implementation of PET imaging into clinical research and, ultimately, clinical routine. To this end, the PET RANO 1.0 criteria are intended to encourage specific investigations of amino acid PET imaging of gliomas
LB  - PUB:(DE-HGF)16
C6  - 38181810
UR  - <Go to ISI:>//WOS:001157190300001
DO  - DOI:10.1016/S1470-2045(23)00525-9
UR  - https://juser.fz-juelich.de/record/1024594
ER  -