001025123 001__ 1025123
001025123 005__ 20240501205652.0
001025123 0247_ $$2datacite_doi$$a10.34734/FZJ-2024-02710
001025123 037__ $$aFZJ-2024-02710
001025123 041__ $$aEnglish
001025123 1001_ $$0P:(DE-Juel1)201210$$aRudani, Binny$$b0
001025123 1112_ $$aBunsen-Tagung 2024$$cAachen$$d2024-03-25 - 2024-03-27$$wGermany
001025123 245__ $$aThermodiffusion of Aqueous Solutions of Guanidinium Salts
001025123 260__ $$c2024
001025123 3367_ $$033$$2EndNote$$aConference Paper
001025123 3367_ $$2BibTeX$$aINPROCEEDINGS
001025123 3367_ $$2DRIVER$$aconferenceObject
001025123 3367_ $$2ORCID$$aCONFERENCE_POSTER
001025123 3367_ $$2DataCite$$aOutput Types/Conference Poster
001025123 3367_ $$0PUB:(DE-HGF)24$$2PUB:(DE-HGF)$$aPoster$$bposter$$mposter$$s1714564052_354$$xOther
001025123 520__ $$aThermodiffusion, or the Ludwig-Soret effect, refers to the motion of solute molecules induced by a thermal gradient. This phenomenon is quantified by the Soret coefficient (ST), in aqueous solutions ST is highly sensitive to the nature of solute-water interactions. It is being used as a tool to probe molecular interactions, mainly protein-ligand binding. Guanidinium ions play a pivotal role in the exploration of protein folding, denaturation, and the hydration of biological molecules owing to its rigid and symmetric structure. Despite its significance, there is a dearth of information on their thermophoretic behaviour. Recent research by our group has delved into the thermodiffusion of similar non-ionic organic solutes and simple ionic inorganic salts in aqueous solutions, revealing distinctive temperature and concentration dependencies of the ST. In our present research, we utilize thermal diffusion forced Rayleigh scattering (TDFRS) to scrutinize guanidinium salt solution with various anions (carbonate, chloride, iodide and thiocyanate), spanning the entire range of the Hofmeister series from hydrophilic to hydrophobic. We performed systematic measurements of ST in a temperature range of 15 to 35°C and concentrations ranging from 0.5m to 3 m. The change of ST withtemperature as a function of increasing concentration becomes weaker for aqueous guanidinium salt solutions. We assume that fewer hydrogen bonds are present at higher concentrations reducing the change of the Soret coefficient and indicatingthat the hydration of the salt plays an important role. Overall, this systematic study helps to gain a fundamental understanding of thermodiffusion in protein-ligand systems.
001025123 536__ $$0G:(DE-HGF)POF4-5241$$a5241 - Molecular Information Processing in Cellular Systems (POF4-524)$$cPOF4-524$$fPOF IV$$x0
001025123 7001_ $$0P:(DE-Juel1)201209$$aJakubowski, Andre$$b1
001025123 7001_ $$0P:(DE-Juel1)131034$$aWiegand, Simone$$b2$$eCorresponding author
001025123 8564_ $$uhttps://juser.fz-juelich.de/record/1025123/files/Bunsen-Tagung%202024%20poster.pdf$$yOpenAccess
001025123 8564_ $$uhttps://juser.fz-juelich.de/record/1025123/files/Bunsen-Tagung%202024%20poster.gif?subformat=icon$$xicon$$yOpenAccess
001025123 8564_ $$uhttps://juser.fz-juelich.de/record/1025123/files/Bunsen-Tagung%202024%20poster.jpg?subformat=icon-1440$$xicon-1440$$yOpenAccess
001025123 8564_ $$uhttps://juser.fz-juelich.de/record/1025123/files/Bunsen-Tagung%202024%20poster.jpg?subformat=icon-180$$xicon-180$$yOpenAccess
001025123 8564_ $$uhttps://juser.fz-juelich.de/record/1025123/files/Bunsen-Tagung%202024%20poster.jpg?subformat=icon-640$$xicon-640$$yOpenAccess
001025123 909CO $$ooai:juser.fz-juelich.de:1025123$$popenaire$$popen_access$$pVDB$$pdriver
001025123 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)201210$$aForschungszentrum Jülich$$b0$$kFZJ
001025123 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)201209$$aForschungszentrum Jülich$$b1$$kFZJ
001025123 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)131034$$aForschungszentrum Jülich$$b2$$kFZJ
001025123 9131_ $$0G:(DE-HGF)POF4-524$$1G:(DE-HGF)POF4-520$$2G:(DE-HGF)POF4-500$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$9G:(DE-HGF)POF4-5241$$aDE-HGF$$bKey Technologies$$lNatural, Artificial and Cognitive Information Processing$$vMolecular and Cellular Information Processing$$x0
001025123 9141_ $$y2024
001025123 915__ $$0StatID:(DE-HGF)0510$$2StatID$$aOpenAccess
001025123 920__ $$lyes
001025123 9201_ $$0I:(DE-Juel1)IBI-4-20200312$$kIBI-4$$lBiomakromolekulare Systeme und Prozesse$$x0
001025123 980__ $$aposter
001025123 980__ $$aVDB
001025123 980__ $$aUNRESTRICTED
001025123 980__ $$aI:(DE-Juel1)IBI-4-20200312
001025123 9801_ $$aFullTexts