guest ::
| Home > Publications database > Insights on the dynamic behavior of protein disulfide isomerase in the solution environment through the SAXS technique > print |
| Home > Publications database > Insights on the dynamic behavior of protein disulfide isomerase in the solution environment through the SAXS technique > print |
| 001 | 1025609 | ||
| 005 | 20250204113844.0 | ||
| 024 | 7 | _ | |a 10.1007/s40203-024-00198-0 |2 doi |
| 037 | _ | _ | |a FZJ-2024-03003 |
| 082 | _ | _ | |a 570 |
| 100 | 1 | _ | |a Sanyasi, Chandrasekar |0 P:(DE-HGF)0 |b 0 |
| 245 | _ | _ | |a Insights on the dynamic behavior of protein disulfide isomerase in the solution environment through the SAXS technique |
| 260 | _ | _ | |a Heidelberg [u.a.] |c 2024 |b SpringerOpen |
| 336 | 7 | _ | |a article |2 DRIVER |
| 336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
| 336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1714725113_29383 |2 PUB:(DE-HGF) |
| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
| 336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 520 | _ | _ | |a The dynamic behavior of Protein Disulfide Isomerase (PDI) in an aqueous solution environment under physiologically active pH has been experimentally verified in this study using Small Angle X-ray Scattering (SAXS) technique. The structural mechanism of dimerization for full-length PDI molecules and co-complex with two renowned substrates has been comprehensively discussed. The structure models obtained from the SAXS data of PDI purified from bovine liver display behavior duality between unaccompanied-enzyme and after engaged with substrates. The analysis of SAXS data revealed that PDI exists as a homo-dimer in the solution environment, and substrate induction provoked its segregation into monomer to enable the enzyme to interact systematically with incoming clients. |
| 536 | _ | _ | |a 5241 - Molecular Information Processing in Cellular Systems (POF4-524) |0 G:(DE-HGF)POF4-5241 |c POF4-524 |f POF IV |x 0 |
| 588 | _ | _ | |a Dataset connected to CrossRef, Journals: juser.fz-juelich.de |
| 700 | 1 | _ | |a Balakrishnan, Susmida Seni |0 P:(DE-HGF)0 |b 1 |
| 700 | 1 | _ | |a Chinnasamy, Thirunavukkarasu |0 P:(DE-HGF)0 |b 2 |
| 700 | 1 | _ | |a Venugopalan, Nagarajan |0 P:(DE-HGF)0 |b 3 |
| 700 | 1 | _ | |a Kandavelu, Palani |0 P:(DE-HGF)0 |b 4 |
| 700 | 1 | _ | |a Batra-Safferling, Renu |0 P:(DE-Juel1)131950 |b 5 |u fzj |
| 700 | 1 | _ | |a Muthuvel, Suresh Kumar |0 P:(DE-HGF)0 |b 6 |e Corresponding author |
| 773 | _ | _ | |a 10.1007/s40203-024-00198-0 |g Vol. 12, no. 1, p. 23 |0 PERI:(DE-600)2702993-1 |n 1 |p 23 |t In Silico Pharmacology |v 12 |y 2024 |x 2193-9616 |
| 909 | C | O | |o oai:juser.fz-juelich.de:1025609 |p VDB |
| 910 | 1 | _ | |a Forschungszentrum Jülich |0 I:(DE-588b)5008462-8 |k FZJ |b 5 |6 P:(DE-Juel1)131950 |
| 913 | 1 | _ | |a DE-HGF |b Key Technologies |l Natural, Artificial and Cognitive Information Processing |1 G:(DE-HGF)POF4-520 |0 G:(DE-HGF)POF4-524 |3 G:(DE-HGF)POF4 |2 G:(DE-HGF)POF4-500 |4 G:(DE-HGF)POF |v Molecular and Cellular Information Processing |9 G:(DE-HGF)POF4-5241 |x 0 |
| 914 | 1 | _ | |y 2024 |
| 915 | _ | _ | |a DEAL Springer |0 StatID:(DE-HGF)3002 |2 StatID |d 2023-09-05 |w ger |
| 915 | _ | _ | |a DEAL Springer |0 StatID:(DE-HGF)3002 |2 StatID |d 2023-09-05 |w ger |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)1190 |2 StatID |b Biological Abstracts |d 2023-09-05 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0300 |2 StatID |b Medline |d 2024-12-18 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0600 |2 StatID |b Ebsco Academic Search |d 2024-12-18 |
| 915 | _ | _ | |a Peer Review |0 StatID:(DE-HGF)0030 |2 StatID |b ASC |d 2024-12-18 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0199 |2 StatID |b Clarivate Analytics Master Journal List |d 2024-12-18 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)1050 |2 StatID |b BIOSIS Previews |d 2024-12-18 |
| 920 | _ | _ | |l yes |
| 920 | 1 | _ | |0 I:(DE-Juel1)IBI-7-20200312 |k IBI-7 |l Strukturbiochemie |x 0 |
| 980 | _ | _ | |a journal |
| 980 | _ | _ | |a VDB |
| 980 | _ | _ | |a I:(DE-Juel1)IBI-7-20200312 |
| 980 | _ | _ | |a UNRESTRICTED |
| Library | Collection | CLSMajor | CLSMinor | Language | Author |
|---|