Gast ::
| Hauptseite > Publikationsdatenbank > Mechanisms of inward transmembrane proton translocation > print |
| Hauptseite > Publikationsdatenbank > Mechanisms of inward transmembrane proton translocation > print |
| 001 | 1025970 | ||
| 005 | 20250203103323.0 | ||
| 024 | 7 | _ | |a 10.1038/s41594-023-01020-9 |2 doi |
| 024 | 7 | _ | |a 1545-9993 |2 ISSN |
| 024 | 7 | _ | |a 1072-8368 |2 ISSN |
| 024 | 7 | _ | |a 1545-9985 |2 ISSN |
| 024 | 7 | _ | |a 2331-365X |2 ISSN |
| 024 | 7 | _ | |a 10.34734/FZJ-2024-03247 |2 datacite_doi |
| 024 | 7 | _ | |a 37386213 |2 pmid |
| 024 | 7 | _ | |a WOS:001020309800001 |2 WOS |
| 037 | _ | _ | |a FZJ-2024-03247 |
| 082 | _ | _ | |a 570 |
| 100 | 1 | _ | |a Kovalev, Kirill |b 0 |
| 245 | _ | _ | |a Mechanisms of inward transmembrane proton translocation |
| 260 | _ | _ | |a London [u.a.] |c 2023 |b Nature Publishing Group |
| 336 | 7 | _ | |a article |2 DRIVER |
| 336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
| 336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1714733385_25114 |2 PUB:(DE-HGF) |
| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
| 336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 520 | _ | _ | |a Proton transport is indispensable for cell life. It is believed that molecular mechanisms of proton movement through different types of proton-conducting molecules have general universal features. However, elucidation of such mechanisms is a challenge. It requires true-atomic-resolution structures of all key proton-conducting states. Here we present a comprehensive function-structure study of a light-driven bacterial inward proton pump, xenorhodopsin, from Bacillus coahuilensis in all major proton-conducting states. The structures reveal that proton translocation is based on proton wires regulated by internal gates. The wires serve as both selectivity filters and translocation pathways for protons. The cumulative results suggest a general concept of proton translocation. We demonstrate the use of serial time-resolved crystallography at a synchrotron source with sub-millisecond resolution for rhodopsin studies, opening the door for principally new applications. The results might also be of interest for optogenetics since xenorhodopsins are the only alternative tools to fire neurons. |
| 536 | _ | _ | |a 5241 - Molecular Information Processing in Cellular Systems (POF4-524) |0 G:(DE-HGF)POF4-5241 |c POF4-524 |f POF IV |x 0 |
| 588 | _ | _ | |a Dataset connected to CrossRef, Journals: juser.fz-juelich.de |
| 700 | 1 | _ | |a Tsybrov, Fedor |0 0000-0001-7422-0899 |b 1 |
| 700 | 1 | _ | |a Alekseev, Alexey |b 2 |
| 700 | 1 | _ | |a Shevchenko, Vitaly |b 3 |
| 700 | 1 | _ | |a Soloviov, Dmytro |0 0000-0001-7945-2218 |b 4 |
| 700 | 1 | _ | |a Siletsky, Sergey |0 P:(DE-HGF)0 |b 5 |
| 700 | 1 | _ | |a Bourenkov, Gleb |0 0000-0002-2617-5920 |b 6 |
| 700 | 1 | _ | |a Agthe, Michael |0 P:(DE-HGF)0 |b 7 |
| 700 | 1 | _ | |a Nikolova, Marina |0 P:(DE-HGF)0 |b 8 |
| 700 | 1 | _ | |a von Stetten, David |0 0000-0001-7906-9788 |b 9 |
| 700 | 1 | _ | |a Astashkin, Roman |0 P:(DE-HGF)0 |b 10 |
| 700 | 1 | _ | |a Bukhdruker, Sergey |0 P:(DE-HGF)0 |b 11 |
| 700 | 1 | _ | |a Chizhov, Igor |0 0000-0001-7744-9365 |b 12 |
| 700 | 1 | _ | |a Royant, Antoine |0 0000-0002-1919-8649 |b 13 |
| 700 | 1 | _ | |a Kuzmin, Alexander |0 0000-0003-3945-3691 |b 14 |
| 700 | 1 | _ | |a Gushchin, Ivan |b 15 |
| 700 | 1 | _ | |a Rosselli, Riccardo |0 0000-0003-1393-0103 |b 16 |
| 700 | 1 | _ | |a Rodriguez-Valera, Francisco |0 0000-0002-9809-2059 |b 17 |
| 700 | 1 | _ | |a Ilyinskiy, Nikolay |0 0000-0002-8812-5849 |b 18 |
| 700 | 1 | _ | |a Rogachev, Andrey |0 P:(DE-HGF)0 |b 19 |
| 700 | 1 | _ | |a Borshchevskiy, Valentin |b 20 |
| 700 | 1 | _ | |a Schneider, Thomas R. |0 0000-0001-6955-7374 |b 21 |
| 700 | 1 | _ | |a Bamberg, Ernst |0 P:(DE-HGF)0 |b 22 |
| 700 | 1 | _ | |a Gordeliy, Valentin |0 P:(DE-Juel1)131964 |b 23 |e Corresponding author |
| 773 | _ | _ | |a 10.1038/s41594-023-01020-9 |g Vol. 30, no. 7, p. 970 - 979 |0 PERI:(DE-600)2131437-8 |n 7 |p 970 - 979 |t Nature structural & molecular biology |v 30 |y 2023 |x 1545-9993 |
| 856 | 4 | _ | |y OpenAccess |u https://juser.fz-juelich.de/record/1025970/files/Kovalev%20et%20al.%20NSMB.pdf |
| 856 | 4 | _ | |y OpenAccess |x icon |u https://juser.fz-juelich.de/record/1025970/files/Kovalev%20et%20al.%20NSMB.gif?subformat=icon |
| 856 | 4 | _ | |y OpenAccess |x icon-1440 |u https://juser.fz-juelich.de/record/1025970/files/Kovalev%20et%20al.%20NSMB.jpg?subformat=icon-1440 |
| 856 | 4 | _ | |y OpenAccess |x icon-180 |u https://juser.fz-juelich.de/record/1025970/files/Kovalev%20et%20al.%20NSMB.jpg?subformat=icon-180 |
| 856 | 4 | _ | |y OpenAccess |x icon-640 |u https://juser.fz-juelich.de/record/1025970/files/Kovalev%20et%20al.%20NSMB.jpg?subformat=icon-640 |
| 909 | C | O | |o oai:juser.fz-juelich.de:1025970 |p openaire |p open_access |p VDB |p driver |p dnbdelivery |
| 910 | 1 | _ | |a Forschungszentrum Jülich |0 I:(DE-588b)5008462-8 |k FZJ |b 23 |6 P:(DE-Juel1)131964 |
| 913 | 1 | _ | |a DE-HGF |b Key Technologies |l Natural, Artificial and Cognitive Information Processing |1 G:(DE-HGF)POF4-520 |0 G:(DE-HGF)POF4-524 |3 G:(DE-HGF)POF4 |2 G:(DE-HGF)POF4-500 |4 G:(DE-HGF)POF |v Molecular and Cellular Information Processing |9 G:(DE-HGF)POF4-5241 |x 0 |
| 914 | 1 | _ | |y 2024 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0200 |2 StatID |b SCOPUS |d 2023-08-23 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0160 |2 StatID |b Essential Science Indicators |d 2023-08-23 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)1050 |2 StatID |b BIOSIS Previews |d 2023-08-23 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)1190 |2 StatID |b Biological Abstracts |d 2023-08-23 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0600 |2 StatID |b Ebsco Academic Search |d 2023-08-23 |
| 915 | _ | _ | |a IF >= 15 |0 StatID:(DE-HGF)9915 |2 StatID |b NAT STRUCT MOL BIOL : 2022 |d 2023-08-23 |
| 915 | _ | _ | |a JCR |0 StatID:(DE-HGF)0100 |2 StatID |b NAT STRUCT MOL BIOL : 2022 |d 2023-08-23 |
| 915 | _ | _ | |a WoS |0 StatID:(DE-HGF)0113 |2 StatID |b Science Citation Index Expanded |d 2023-08-23 |
| 915 | _ | _ | |a DEAL Nature |0 StatID:(DE-HGF)3003 |2 StatID |d 2023-08-23 |w ger |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)1030 |2 StatID |b Current Contents - Life Sciences |d 2023-08-23 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0150 |2 StatID |b Web of Science Core Collection |d 2023-08-23 |
| 915 | _ | _ | |a OpenAccess |0 StatID:(DE-HGF)0510 |2 StatID |
| 915 | _ | _ | |a Peer Review |0 StatID:(DE-HGF)0030 |2 StatID |b ASC |d 2023-08-23 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0300 |2 StatID |b Medline |d 2023-08-23 |
| 915 | _ | _ | |a Nationallizenz |0 StatID:(DE-HGF)0420 |2 StatID |d 2023-08-23 |w ger |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0199 |2 StatID |b Clarivate Analytics Master Journal List |d 2023-08-23 |
| 920 | _ | _ | |l yes |
| 920 | 1 | _ | |0 I:(DE-Juel1)IBI-7-20200312 |k IBI-7 |l Strukturbiochemie |x 0 |
| 980 | _ | _ | |a journal |
| 980 | _ | _ | |a VDB |
| 980 | _ | _ | |a UNRESTRICTED |
| 980 | _ | _ | |a I:(DE-Juel1)IBI-7-20200312 |
| 980 | 1 | _ | |a FullTexts |
| Library | Collection | CLSMajor | CLSMinor | Language | Author |
|---|