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| Hauptseite > Publikationsdatenbank > Common neural dysfunction of economic decision-making across psychiatric conditions > print |
| Hauptseite > Publikationsdatenbank > Common neural dysfunction of economic decision-making across psychiatric conditions > print |
| 001 | 1026362 | ||
| 005 | 20250204113855.0 | ||
| 024 | 7 | _ | |a 10.1016/j.neuroimage.2024.120641 |2 doi |
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| 100 | 1 | _ | |a Feng, Chunliang |0 P:(DE-HGF)0 |b 0 |e Corresponding author |
| 245 | _ | _ | |a Common neural dysfunction of economic decision-making across psychiatric conditions |
| 260 | _ | _ | |a Orlando, Fla. |c 2024 |b Academic Press |
| 336 | 7 | _ | |a article |2 DRIVER |
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| 520 | _ | _ | |a Adaptive decision-making, which is often impaired in various psychiatric conditions, is essential for well-being. Recent evidence has indicated that decision-making capacity in multiple tasks could be accounted for by latent dimensions, enlightening the question of whether there is a common disruption of brain networks in economic decision-making across psychiatric conditions. Here, we addressed the issue by combining activation/lesion network mapping analyses with a transdiagnostic brain imaging meta-analysis. Our findings indicate that there were transdiagnostic alterations in the thalamus and ventral striatum during the decision or outcome stage of decision-making. The identified regions represent key nodes in a large-scale network, which is composed of multiple heterogeneous brain regions and plays a causal role in motivational functioning. The findings suggest that disturbances in the network associated with emotion- and reward-related processing play a key role in dysfunctions of decision‐making observed in various psychiatric conditions. This study provides the first meta-analytic evidence of common neural alterations linked to deficits in economic decision-making. |
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| 700 | 1 | _ | |a Li, Ting |0 P:(DE-HGF)0 |b 3 |
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| 700 | 1 | _ | |a Qu, Chen |0 P:(DE-HGF)0 |b 7 |e Corresponding author |
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