001026452 001__ 1026452
001026452 005__ 20240521214524.0
001026452 0247_ $$2doi$$a10.1101/2024.05.04.592501
001026452 0247_ $$2datacite_doi$$a10.34734/FZJ-2024-03401
001026452 037__ $$aFZJ-2024-03401
001026452 082__ $$a570
001026452 1001_ $$0P:(DE-Juel1)191294$$aSerio, Bianca$$b0$$ufzj
001026452 245__ $$aExploring sex-specific neuroendocrine influences on the sensorimotor-association axis in single individuals
001026452 260__ $$aCold Spring Harbor$$bCold Spring Harbor Laboratory, NY$$c2024
001026452 3367_ $$0PUB:(DE-HGF)25$$2PUB:(DE-HGF)$$aPreprint$$bpreprint$$mpreprint$$s1716272441_9025
001026452 3367_ $$2ORCID$$aWORKING_PAPER
001026452 3367_ $$028$$2EndNote$$aElectronic Article
001026452 3367_ $$2DRIVER$$apreprint
001026452 3367_ $$2BibTeX$$aARTICLE
001026452 3367_ $$2DataCite$$aOutput Types/Working Paper
001026452 520__ $$aHuman neuroimaging studies consistently show multimodal patterns of variability along a key principle of macroscale cortical organization – the sensorimotor-association (S-A) axis. However, little is known about day-to-day fluctuations in functional activity along this axis within an individual, including sex-specific neuroendocrine factors contributing to such transient changes. We leveraged data from two densely sampled healthy young adults, one female and one male, to investigate intra-individual daily variability along the S-A axis, which we computed as our measure of functional cortical organization by reducing the dimensionality of functional connectivity matrices. Daily variability was greatest in temporal limbic and ventral prefrontal regions in both participants, and was more strongly pronounced in the male subject. Next, we probed local and system-level effects of steroid hormones and self-reported perceived stress on functional organization. Our findings revealed modest effects that differed between participants, hinting at subtle –potentially sex-specific– associations between neuroendocrine fluctuations and intra-individual variability along the S-A axis. In sum, our study points to neuroendocrine factors as possible modulators of intra-individual variability in functional brain organization, highlighting the need for further research in larger samples.
001026452 536__ $$0G:(DE-HGF)POF4-5251$$a5251 - Multilevel Brain Organization and Variability (POF4-525)$$cPOF4-525$$fPOF IV$$x0
001026452 588__ $$aDataset connected to CrossRef
001026452 7001_ $$0P:(DE-Juel1)203209$$aYilmaz, Deniz$$b1$$ufzj
001026452 7001_ $$0P:(DE-HGF)0$$aPritschet, Laura$$b2
001026452 7001_ $$0P:(DE-HGF)0$$aGrotzinger, Hannah$$b3
001026452 7001_ $$0P:(DE-HGF)0$$aJacobs, Emily G.$$b4
001026452 7001_ $$0P:(DE-Juel1)131678$$aEickhoff, Simon B.$$b5$$ufzj
001026452 7001_ $$0P:(DE-Juel1)173843$$aValk, Sofie L.$$b6$$ufzj
001026452 773__ $$0PERI:(DE-600)2766415-6$$a10.1101/2024.05.04.592501$$tbioRxiv beta$$y2024
001026452 8564_ $$uhttps://juser.fz-juelich.de/record/1026452/files/2024.05.04.592501.full.pdf$$yOpenAccess
001026452 8564_ $$uhttps://juser.fz-juelich.de/record/1026452/files/2024.05.04.592501.full.gif?subformat=icon$$xicon$$yOpenAccess
001026452 8564_ $$uhttps://juser.fz-juelich.de/record/1026452/files/2024.05.04.592501.full.jpg?subformat=icon-1440$$xicon-1440$$yOpenAccess
001026452 8564_ $$uhttps://juser.fz-juelich.de/record/1026452/files/2024.05.04.592501.full.jpg?subformat=icon-180$$xicon-180$$yOpenAccess
001026452 8564_ $$uhttps://juser.fz-juelich.de/record/1026452/files/2024.05.04.592501.full.jpg?subformat=icon-640$$xicon-640$$yOpenAccess
001026452 909CO $$ooai:juser.fz-juelich.de:1026452$$popenaire$$popen_access$$pVDB$$pdriver$$pdnbdelivery
001026452 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)191294$$aForschungszentrum Jülich$$b0$$kFZJ
001026452 9101_ $$0I:(DE-HGF)0$$6P:(DE-Juel1)191294$$a Max Planck School of Cognition, Leipzig$$b0
001026452 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)203209$$aForschungszentrum Jülich$$b1$$kFZJ
001026452 9101_ $$0I:(DE-HGF)0$$6P:(DE-Juel1)203209$$a Max Planck School of Cognition, Leipzig$$b1
001026452 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)131678$$aForschungszentrum Jülich$$b5$$kFZJ
001026452 9101_ $$0I:(DE-HGF)0$$6P:(DE-Juel1)131678$$a HHU Düsseldorf$$b5
001026452 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)173843$$aForschungszentrum Jülich$$b6$$kFZJ
001026452 9131_ $$0G:(DE-HGF)POF4-525$$1G:(DE-HGF)POF4-520$$2G:(DE-HGF)POF4-500$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$9G:(DE-HGF)POF4-5251$$aDE-HGF$$bKey Technologies$$lNatural, Artificial and Cognitive Information Processing$$vDecoding Brain Organization and Dysfunction$$x0
001026452 9141_ $$y2024
001026452 915__ $$0StatID:(DE-HGF)0510$$2StatID$$aOpenAccess
001026452 920__ $$lyes
001026452 9201_ $$0I:(DE-Juel1)INM-7-20090406$$kINM-7$$lGehirn & Verhalten$$x0
001026452 980__ $$apreprint
001026452 980__ $$aVDB
001026452 980__ $$aUNRESTRICTED
001026452 980__ $$aI:(DE-Juel1)INM-7-20090406
001026452 9801_ $$aFullTexts