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| Hauptseite > Publikationsdatenbank > Radiomics workflow definition & challenges - German priority program 2177 consensus statement on clinically applied radiomics > print |
| Hauptseite > Publikationsdatenbank > Radiomics workflow definition & challenges - German priority program 2177 consensus statement on clinically applied radiomics > print |
| 001 | 1027017 | ||
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| 024 | 7 | _ | |a 10.1186/s13244-024-01704-w |2 doi |
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| 100 | 1 | _ | |a Floca, Ralf |0 P:(DE-HGF)0 |b 0 |e Corresponding author |
| 245 | _ | _ | |a Radiomics workflow definition & challenges - German priority program 2177 consensus statement on clinically applied radiomics |
| 260 | _ | _ | |a Heidelberg |c 2024 |b Springer |
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| 500 | _ | _ | |a Funded by the DFG 428090865, 428149221, 428210203, 428212052, 428212161, 428215948, 428216905, 428218324, 428219815, 428222922, 428223038, 428223139, 428223917, 428224258, 428224476 / SPP 2177 • Partially funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) – Projektnummer 442326535 / |
| 520 | _ | _ | |a Objectives: Achieving a consensus on a definition for different aspects of radiomics workflows to support their translation into clinical usage. Furthermore, to assess the perspective of experts on important challenges for a successful clinical workflow implementation.Materials and methods: The consensus was achieved by a multi-stage process. Stage 1 comprised a definition screening, a retrospective analysis with semantic mapping of terms found in 22 workflow definitions, and the compilation of an initial baseline definition. Stages 2 and 3 consisted of a Delphi process with over 45 experts hailing from sites participating in the German Research Foundation (DFG) Priority Program 2177. Stage 2 aimed to achieve a broad consensus for a definition proposal, while stage 3 identified the importance of translational challenges.Results: Workflow definitions from 22 publications (published 2012-2020) were analyzed. Sixty-nine definition terms were extracted, mapped, and semantic ambiguities (e.g., homonymous and synonymous terms) were identified and resolved. The consensus definition was developed via a Delphi process. The final definition comprising seven phases and 37 aspects reached a high overall consensus (> 89% of experts "agree" or "strongly agree"). Two aspects reached no strong consensus. In addition, the Delphi process identified and characterized from the participating experts' perspective the ten most important challenges in radiomics workflows.Conclusion: To overcome semantic inconsistencies between existing definitions and offer a well-defined, broad, referenceable terminology, a consensus workflow definition for radiomics-based setups and a terms mapping to existing literature was compiled. Moreover, the most relevant challenges towards clinical application were characterized.Critical relevance statement: Lack of standardization represents one major obstacle to successful clinical translation of radiomics. Here, we report a consensus workflow definition on different aspects of radiomics studies and highlight important challenges to advance the clinical adoption of radiomics.Key points: Published radiomics workflow terminologies are inconsistent, hindering standardization and translation. A consensus radiomics workflow definition proposal with high agreement was developed. Publicly available result resources for further exploitation by the scientific community.Keywords: Computer-assisted; Consensus development conference; Image processing; Terminology; Workflow. |
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| 536 | _ | _ | |a DFG project 428090865 - Radiomics basierend auf MRT und Aminosäure PET in der Neuroonkologie (428090865) |0 G:(GEPRIS)428090865 |c 428090865 |x 1 |
| 536 | _ | _ | |a DFG project 428149221 - Prädiktion von Therapieansprechen und Outcome beim lokal fortgeschrittenen Rektum-Karzinom mittels Radiomics und Deep Learning: eine beispielhafte Anwendung für eine allgemein verwendbare, Deep Learning basierte Prozessierungs-Pipeline für die Bild-Klassifikation. (428149221) |0 G:(GEPRIS)428149221 |c 428149221 |x 2 |
| 536 | _ | _ | |a DFG project 428210203 - Bildmorphologische Biomarker der menschlichen Skelettmuskulatur (Muskelmasse, morphologische und Textureigenschaften von Muskelgruppen des Körperstamms und Oberschenkels) bei Sarkopenie und kardiometabolischen Erkrankungen (428210203) |0 G:(GEPRIS)428210203 |c 428210203 |x 3 |
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