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@INPROCEEDINGS{Shabani:1027080,
author = {Shabani, Doruntin and Lange, Christoph and Butzek, Michael
and Strub, Erik and Michel, Marco and Gutberlet, Thomas and
Mauerhofer, Eric and Walther, Clemens and Ohm, David and
Dragoun, Andreas},
title = {{I}nnovative approach for sustainable and low-waste
production of99{M}o-based radiodiagnostics using
accelerator-based neutron source},
reportid = {FZJ-2024-03632},
year = {2024},
abstract = {Nuclear medicine diagnostics that are integral to modern
healthcare, heavily rely on the radionuclide99Mo,
traditionally produced in nuclear reactors through the
fission of 235U [1, 2,3]. However, the complex radiochemical
processing involved generates substantial radioactivewaste,
necessitating a shift towards more sustainable practices.
This poster presents the99Mo Best joint project, an
initiative focused on developing an innovative,
cost-efficient conceptfor the production and utilization of
99Mo-based radiodiagnostics, utilizing the 98Mo(n,γ)99Mo
reaction eliminating fissile materials and minimizing
radioactive waste.The project comprises three key
sub-projects:1. Process Optimization: This involves refining
the processes for generating 99Mo-basedradiodiagnostics, as
well as improving their processing and utilization in
clinical settings.2. Neutron Target Technology: Developing
high neutron flux density neutron target technologyis
crucial for irradiation with reduced radiation doses,
ensuring safe handling andprocessing of Mo samples
post-irradiation.3. Radiation Protection and Disposal:
Addressing safety concerns, this sub-project aims
todetermine radiation protection and disposal issues
pertinent to the novel 99Mo productionprocess, ensuring a
secure and sustainable approach.This comprehensive approach
aims to create a paradigm shift in the field of nuclear
medicineby offering a sustainable and efficient alternative
to traditional 99Mo production methods,mitigating
environmental impact and advancing the application of
accelerator-based neutronradiation sources in medical
radioisotope production.AcknowledmentsThis work is supported
by the German Federal Ministry of Education and Research
(BMBF) underGrant No. 02NUK080B.References1. NEA (2019),
“The Supply of Medical Radioisotopes: 2019 Medical Isotope
Demand and Capacity2. Projection for the 2019–2024
Period”, OECD Publishing, Paris.3. Deutscher Bundestag,
Drucksache 17/3142, 2010.4. Jaroszewicz J, Marcinkowska Z,
Pytel K (2014) Production of fission product 99Mo using
highenricheduranium plates in Polish nuclear research
reactor MARIA: Technology and neutronicanalysis. Nukleonika
59(2):43–52.},
month = {May},
date = {2024-05-05},
organization = {International Conference on Modern
Trends in Activation Analysis, MERCURE
BUDA CASTLE HILL BUDAPEST (Hungary), 5
May 2024 - 10 May 2024},
subtyp = {Invited},
cin = {JCNS-2 / JCNS-HBS / ZEA-1 / JARA-FIT / INM-5},
cid = {I:(DE-Juel1)JCNS-2-20110106 / I:(DE-Juel1)JCNS-HBS-20180709
/ I:(DE-Juel1)ZEA-1-20090406 / $I:(DE-82)080009_20140620$ /
I:(DE-Juel1)INM-5-20090406},
pnm = {632 - Materials – Quantum, Complex and Functional
Materials (POF4-632) / 6G4 - Jülich Centre for Neutron
Research (JCNS) (FZJ) (POF4-6G4)},
pid = {G:(DE-HGF)POF4-632 / G:(DE-HGF)POF4-6G4},
typ = {PUB:(DE-HGF)24},
url = {https://juser.fz-juelich.de/record/1027080},
}