TY  - JOUR
AU  - Nehls, Susanne
AU  - Dukart, Jürgen
AU  - Enzensberger, Christian
AU  - Stickeler, Elmar
AU  - Eickhoff, Simon B.
AU  - Chechko, Natalia
TI  - Vorhersage und frühzeitige Identifikation einer postpartalen Depression: Ergebnisse der longitudinalen RiPoD-Studie im Kontext der LiteraturPrediction and timely identification of postpartum depression: results of the longitudinal RiPoD study in the context of the literature
JO  - Der Nervenarzt
VL  - 96
SN  - 0028-2804
CY  - Heidelberg
PB  - Springer
M1  - FZJ-2024-05373
SP  - 176–184
PY  - 2025
AB  - The first 4-6 weeks after childbirth are defined as the onset time for postpartum depression (PPD). Despite this known time frame there are significant gaps in the identification and treatment of PPD. The risk for postpartum depression (RiPoD) study investigated specific risk factors and predictors of postpartum psychological adjustment processes and the results are presented within the framework of a state of the art review of research. The dynamic neuroplastic changes in the maternal brain during pregnancy and the postpartum period appear to be closely linked to peripartum hormone fluctuations, which jointly influence the development of postpartum mood disorders. Hormonal risk factors such as baby blues and premenstrual syndrome have been found to have a bearing on PPD. The combination of these two factors predicts the risk of PPD with 83% sensitivity within the first week postpartum. Follow-up digital monitoring of symptom development in the first 6 weeks postpartum has enabled an accurate identification of women with PPD. Understanding the interaction between hormone fluctuations, neuroplasticity and psychiatric disorders should be an important target for future research. Early identification and diagnosis of PPD can be easily integrated into the clinical routine and everyday life.
LB  - PUB:(DE-HGF)16
C6  - 39186106
UR  - <Go to ISI:>//WOS:001298719000001
DO  - DOI:10.1007/s00115-024-01726-1
UR  - https://juser.fz-juelich.de/record/1030649
ER  -