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@ARTICLE{Nehls:1030649,
author = {Nehls, Susanne and Dukart, Jürgen and Enzensberger,
Christian and Stickeler, Elmar and Eickhoff, Simon B. and
Chechko, Natalia},
title = {{V}orhersage und frühzeitige {I}dentifikation einer
postpartalen {D}epression: {E}rgebnisse der longitudinalen
{R}i{P}o{D}-{S}tudie im {K}ontext der
{L}iteratur{P}rediction and timely identification of
postpartum depression: results of the longitudinal
{R}i{P}o{D} study in the context of the literature},
journal = {Der Nervenarzt},
volume = {96},
issn = {0028-2804},
address = {Heidelberg},
publisher = {Springer},
reportid = {FZJ-2024-05373},
pages = {176–184},
year = {2025},
abstract = {The first 4-6 weeks after childbirth are defined as the
onset time for postpartum depression (PPD). Despite this
known time frame there are significant gaps in the
identification and treatment of PPD. The risk for postpartum
depression (RiPoD) study investigated specific risk factors
and predictors of postpartum psychological adjustment
processes and the results are presented within the framework
of a state of the art review of research. The dynamic
neuroplastic changes in the maternal brain during pregnancy
and the postpartum period appear to be closely linked to
peripartum hormone fluctuations, which jointly influence the
development of postpartum mood disorders. Hormonal risk
factors such as baby blues and premenstrual syndrome have
been found to have a bearing on PPD. The combination of
these two factors predicts the risk of PPD with $83\%$
sensitivity within the first week postpartum. Follow-up
digital monitoring of symptom development in the first 6
weeks postpartum has enabled an accurate identification of
women with PPD. Understanding the interaction between
hormone fluctuations, neuroplasticity and psychiatric
disorders should be an important target for future research.
Early identification and diagnosis of PPD can be easily
integrated into the clinical routine and everyday life.},
cin = {INM-7 / INM-10},
ddc = {610},
cid = {I:(DE-Juel1)INM-7-20090406 / I:(DE-Juel1)INM-10-20170113},
pnm = {5251 - Multilevel Brain Organization and Variability
(POF4-525)},
pid = {G:(DE-HGF)POF4-5251},
typ = {PUB:(DE-HGF)16},
pubmed = {39186106},
UT = {WOS:001298719000001},
doi = {10.1007/s00115-024-01726-1},
url = {https://juser.fz-juelich.de/record/1030649},
}