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@ARTICLE{Serio:1030754,
      author       = {Serio, Bianca and Hettwer, Meike D. and Wiersch, Lisa and
                      Bignardi, Giacomo and Sacher, Julia and Weis, Susanne and
                      Eickhoff, Simon B. and Valk, Sofie L.},
      title        = {{S}ex differences in functional cortical organization
                      reflect differences in network topology rather than cortical
                      morphometry},
      journal      = {Nature Communications},
      volume       = {15},
      number       = {1},
      issn         = {2041-1723},
      address      = {[London]},
      publisher    = {Nature Publishing Group UK},
      reportid     = {FZJ-2024-05457},
      pages        = {7714},
      year         = {2024},
      abstract     = {Differences in brain size between the sexes are
                      consistently reported. However, the consequences of this
                      anatomical difference on sex differences in intrinsic brain
                      function remain unclear. In the current study, we
                      investigate whether sex differences in intrinsic cortical
                      functional organization may be associated with differences
                      in cortical morphometry, namely different measures of brain
                      size, microstructure, and the geodesic distance of
                      connectivity profiles. For this, we compute a low
                      dimensional representation of functional cortical
                      organization, the sensory-association axis, and identify
                      widespread sex differences. Contrary to our expectations,
                      sex differences in functional organization do not appear to
                      be systematically associated with differences in total
                      surface area, microstructural organization, or geodesic
                      distance, despite these morphometric properties being per se
                      associated with functional organization and differing
                      between sexes. Instead, functional sex differences in the
                      sensory-association axis are associated with differences in
                      functional connectivity profiles and network topology.
                      Collectively, our findings suggest that sex differences in
                      functional cortical organization extend beyond sex
                      differences in cortical morphometry.},
      cin          = {INM-7},
      ddc          = {500},
      cid          = {I:(DE-Juel1)INM-7-20090406},
      pnm          = {5251 - Multilevel Brain Organization and Variability
                      (POF4-525)},
      pid          = {G:(DE-HGF)POF4-5251},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {39231965},
      UT           = {WOS:001335948800015},
      doi          = {10.1038/s41467-024-51942-1},
      url          = {https://juser.fz-juelich.de/record/1030754},
}