Lecture (Invited) FZJ-2024-05675

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Making the multiscale organization of the human brain accessible to reproducible workflows using siibra-python

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2024

Lecture at 8th BigBrain Workshop (Padua, Italy), 9 Sep 2024 - 11 Sep 20242024-09-092024-09-11

Abstract: Understanding the human brain requires access to experimental data that capture relevant aspects of brain organization across a broad range of scales and modalities, and typically originate from a plethora of resources. To make multimodal and multidimensional measures of brain organization accessible, they need to be integrated into a common reference framework and exposed via suitable software interfaces. This tutorial will introduce participants to siibra toolsuite, which provides access to a multilevel atlas of the human brain built from “big data”. The atlas integrates brain reference templates at different spatial scales, complementary parcellation maps, and a wide range of multimodal data features. It links macroanatomical concepts and their inter-subject variability with measurements of the microstructural composition and intrinsic variance of brain regions, using cytoarchitectonic maps as a reference, and integrating the BigBrain model as microscopic reference template. The tool suite includes a web-based 3D viewer (siibra-explorer) and a Python library (siibra-python) to support a broad range of neuroscientific use cases. It makes use of EBRAINS as a data sharing platform and cloud infrastructure and implements interfaces to other neuroscience resources. The focus of this tutorial will be on building reproducible workflows with BigBrain data using the siibra-python library.


Contributing Institute(s):
  1. Strukturelle und funktionelle Organisation des Gehirns (INM-1)
Research Program(s):
  1. 5251 - Multilevel Brain Organization and Variability (POF4-525) (POF4-525)
  2. 5254 - Neuroscientific Data Analytics and AI (POF4-525) (POF4-525)
  3. HIBALL - Helmholtz International BigBrain Analytics and Learning Laboratory (HIBALL) (InterLabs-0015) (InterLabs-0015)
  4. EBRAINS 2.0 - EBRAINS 2.0: A Research Infrastructure to Advance Neuroscience and Brain Health (101147319) (101147319)
  5. Helmholtz AI - Helmholtz Artificial Intelligence Coordination Unit – Local Unit FZJ (E.40401.62) (E.40401.62)

Appears in the scientific report 2024
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 Record created 2024-09-26, last modified 2024-11-07


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