001032442 001__ 1032442
001032442 005__ 20250203133219.0
001032442 0247_ $$2doi$$a10.1186/s42466-024-00350-3
001032442 0247_ $$2datacite_doi$$a10.34734/FZJ-2024-06248
001032442 0247_ $$2pmid$$a39472968
001032442 0247_ $$2WOS$$aWOS:001344817300001
001032442 037__ $$aFZJ-2024-06248
001032442 082__ $$a610
001032442 1001_ $$00000-0002-1868-440X$$aGoerttler, Tsepo$$b0$$eCorresponding author
001032442 245__ $$aIatrogenic botulism after intragastric botulinum neurotoxin injections – a major outbreak
001032442 260__ $$a[London]$$bBioMed Central$$c2024
001032442 3367_ $$2DRIVER$$aarticle
001032442 3367_ $$2DataCite$$aOutput Types/Journal article
001032442 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1731654717_17956
001032442 3367_ $$2BibTeX$$aARTICLE
001032442 3367_ $$2ORCID$$aJOURNAL_ARTICLE
001032442 3367_ $$00$$2EndNote$$aJournal Article
001032442 500__ $$aSupported by the DFG in the framework of the DFG Clinician Scientist Programme UMEA, FU356/12-2
001032442 520__ $$aAbstractBackgroundIntragastric botulinum neurotoxin injections (IBNI) are offered off-label in the private medical sector in a few European countries as a safe and effective weight-loss measure. In February and March 2023, an outbreak of iatrogenic botulism occurred in several European countries following IBNI treatment in Turkey. This case series describes the clinical features of severe iatrogenic botulism after IBNI.MethodsWe retrospectively summarize the clinical course and emergency department and intensive care unit interventions in ten cases of severe iatrogenic botulism that occurred after receiving IBNI in this sudden outbreak in Austria and Germany.ResultsSeven out of ten cases initially showed characteristic symptoms of botulism with diplopia, dysphagia, dysarthria, dysarthrophonia, and descending paralysis. All patients were hospitalized, six in an intensive care unit and partially requiring mechanical ventilation. All patients recovered and were discharged without relevant permanent deficits.ConclusionOur study highlights ten clinical cases in this iatrogenic botulism outbreak, representing the largest reported outbreak worldwide. Clinicians should be aware of the risks associated with medical procedures involving botulinum neurotoxins and ensure measures to minimize the risk of iatrogenic botulism.
001032442 536__ $$0G:(DE-HGF)POF4-5251$$a5251 - Multilevel Brain Organization and Variability (POF4-525)$$cPOF4-525$$fPOF IV$$x0
001032442 588__ $$aDataset connected to CrossRef, Journals: juser.fz-juelich.de
001032442 7001_ $$0P:(DE-HGF)0$$aDorner, Martin B.$$b1
001032442 7001_ $$0P:(DE-HGF)0$$avan der Linden, Christina$$b2
001032442 7001_ $$0P:(DE-HGF)0$$aKienitz, Ricardo$$b3
001032442 7001_ $$0P:(DE-HGF)0$$aPetrik, Stephan$$b4
001032442 7001_ $$aBlechinger, Stephan$$b5
001032442 7001_ $$aSpickschen, Jonah$$b6
001032442 7001_ $$aBetz, Iris R.$$b7
001032442 7001_ $$aHinrichs, Carl$$b8
001032442 7001_ $$aSteindl, David$$b9
001032442 7001_ $$0P:(DE-Juel1)176463$$aWeber, Frederike$$b10
001032442 7001_ $$aMusacchio, Thomas$$b11
001032442 7001_ $$aWunderlich, Gilbert$$b12
001032442 7001_ $$aRueger, Maria Adele$$b13
001032442 7001_ $$0P:(DE-Juel1)131613$$aBarbe, Michael T.$$b14
001032442 7001_ $$aDafsari, Haidar$$b15
001032442 7001_ $$aDemir, Seda$$b16
001032442 7001_ $$aLapa, Sriramya$$b17
001032442 7001_ $$aZeiner, Pia S.$$b18
001032442 7001_ $$aStrzelczyk, Adam$$b19
001032442 7001_ $$aTinnemann, Peter$$b20
001032442 7001_ $$aKleine, Christian$$b21
001032442 7001_ $$aTotzeck, Andreas$$b22
001032442 7001_ $$aKlebe, Stephan$$b23
001032442 7001_ $$aMikolajewska, Agata$$b24
001032442 7001_ $$aDorner, Brigitte G.$$b25
001032442 7001_ $$aFertl, Elisabeth$$b26
001032442 7001_ $$aGrefkes-Hermann, Christian$$b27
001032442 7001_ $$0P:(DE-Juel1)131720$$aFink, Gereon$$b28
001032442 7001_ $$0P:(DE-HGF)0$$aKleinschnitz, Christoph$$b29
001032442 7001_ $$0P:(DE-HGF)0$$aHagenacker, Tim$$b30
001032442 773__ $$0PERI:(DE-600)2947493-0$$a10.1186/s42466-024-00350-3$$gVol. 6, no. 1, p. 52$$n1$$p52$$tNeurological research and practice$$v6$$x2524-3489$$y2024
001032442 8564_ $$uhttps://juser.fz-juelich.de/record/1032442/files/PDF.pdf$$yOpenAccess
001032442 909CO $$ooai:juser.fz-juelich.de:1032442$$pdnbdelivery$$pdriver$$pVDB$$popen_access$$popenaire
001032442 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)176463$$aForschungszentrum Jülich$$b10$$kFZJ
001032442 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)131720$$aForschungszentrum Jülich$$b28$$kFZJ
001032442 9131_ $$0G:(DE-HGF)POF4-525$$1G:(DE-HGF)POF4-520$$2G:(DE-HGF)POF4-500$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$9G:(DE-HGF)POF4-5251$$aDE-HGF$$bKey Technologies$$lNatural, Artificial and Cognitive Information Processing$$vDecoding Brain Organization and Dysfunction$$x0
001032442 9141_ $$y2024
001032442 915__ $$0LIC:(DE-HGF)CCBY4$$2HGFVOC$$aCreative Commons Attribution CC BY 4.0
001032442 915__ $$0StatID:(DE-HGF)0510$$2StatID$$aOpenAccess
001032442 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS$$d2024-12-30
001032442 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline$$d2024-12-30
001032442 915__ $$0StatID:(DE-HGF)0501$$2StatID$$aDBCoverage$$bDOAJ Seal$$d2024-04-10T15:42:53Z
001032442 915__ $$0StatID:(DE-HGF)0500$$2StatID$$aDBCoverage$$bDOAJ$$d2024-04-10T15:42:53Z
001032442 915__ $$0StatID:(DE-HGF)0030$$2StatID$$aPeer Review$$bDOAJ : Anonymous peer review$$d2024-04-10T15:42:53Z
001032442 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List$$d2024-12-30
001032442 915__ $$0StatID:(DE-HGF)0112$$2StatID$$aWoS$$bEmerging Sources Citation Index$$d2024-12-30
001032442 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection$$d2024-12-30
001032442 920__ $$lyes
001032442 9201_ $$0I:(DE-Juel1)INM-3-20090406$$kINM-3$$lKognitive Neurowissenschaften$$x0
001032442 980__ $$ajournal
001032442 980__ $$aVDB
001032442 980__ $$aUNRESTRICTED
001032442 980__ $$aI:(DE-Juel1)INM-3-20090406
001032442 9801_ $$aFullTexts