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@ARTICLE{Goerttler:1032442,
      author       = {Goerttler, Tsepo and Dorner, Martin B. and van der Linden,
                      Christina and Kienitz, Ricardo and Petrik, Stephan and
                      Blechinger, Stephan and Spickschen, Jonah and Betz, Iris R.
                      and Hinrichs, Carl and Steindl, David and Weber, Frederike
                      and Musacchio, Thomas and Wunderlich, Gilbert and Rueger,
                      Maria Adele and Barbe, Michael T. and Dafsari, Haidar and
                      Demir, Seda and Lapa, Sriramya and Zeiner, Pia S. and
                      Strzelczyk, Adam and Tinnemann, Peter and Kleine, Christian
                      and Totzeck, Andreas and Klebe, Stephan and Mikolajewska,
                      Agata and Dorner, Brigitte G. and Fertl, Elisabeth and
                      Grefkes-Hermann, Christian and Fink, Gereon and
                      Kleinschnitz, Christoph and Hagenacker, Tim},
      title        = {{I}atrogenic botulism after intragastric botulinum
                      neurotoxin injections – a major outbreak},
      journal      = {Neurological research and practice},
      volume       = {6},
      number       = {1},
      issn         = {2524-3489},
      address      = {[London]},
      publisher    = {BioMed Central},
      reportid     = {FZJ-2024-06248},
      pages        = {52},
      year         = {2024},
      note         = {Supported by the DFG in the framework of the DFG Clinician
                      Scientist Programme UMEA, FU356/12-2},
      abstract     = {AbstractBackgroundIntragastric botulinum neurotoxin
                      injections (IBNI) are offered off-label in the private
                      medical sector in a few European countries as a safe and
                      effective weight-loss measure. In February and March 2023,
                      an outbreak of iatrogenic botulism occurred in several
                      European countries following IBNI treatment in Turkey. This
                      case series describes the clinical features of severe
                      iatrogenic botulism after IBNI.MethodsWe retrospectively
                      summarize the clinical course and emergency department and
                      intensive care unit interventions in ten cases of severe
                      iatrogenic botulism that occurred after receiving IBNI in
                      this sudden outbreak in Austria and Germany.ResultsSeven out
                      of ten cases initially showed characteristic symptoms of
                      botulism with diplopia, dysphagia, dysarthria,
                      dysarthrophonia, and descending paralysis. All patients were
                      hospitalized, six in an intensive care unit and partially
                      requiring mechanical ventilation. All patients recovered and
                      were discharged without relevant permanent
                      deficits.ConclusionOur study highlights ten clinical cases
                      in this iatrogenic botulism outbreak, representing the
                      largest reported outbreak worldwide. Clinicians should be
                      aware of the risks associated with medical procedures
                      involving botulinum neurotoxins and ensure measures to
                      minimize the risk of iatrogenic botulism.},
      cin          = {INM-3},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-3-20090406},
      pnm          = {5251 - Multilevel Brain Organization and Variability
                      (POF4-525)},
      pid          = {G:(DE-HGF)POF4-5251},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {39472968},
      UT           = {WOS:001344817300001},
      doi          = {10.1186/s42466-024-00350-3},
      url          = {https://juser.fz-juelich.de/record/1032442},
}