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@ARTICLE{Jergas:1032448,
author = {Jergas, Hannah and Steffen, Julia K. and Schedlich-Teufer,
Charlotte and Strelow, Joshua N. and Kramme, Johanna and
Fink, Gereon R. and Visser-Vandewalle, Veerle and Barbe,
Michael T. and Wirths, Jochen},
title = {{V}ideo-{G}uided {O}ptimization of {S}timulation {S}ettings
in {P}atients with {P}arkinson’s {D}isease and {D}eep
{B}rain {S}timulation},
journal = {Brain Sciences},
volume = {14},
number = {9},
issn = {2076-3425},
address = {Basel},
publisher = {MDPI AG},
reportid = {FZJ-2024-06254},
pages = {914 -},
year = {2024},
abstract = {Deep brain stimulation (DBS) for Parkinson's disease (PD)
often necessitates frequent clinic visits for stimulation
program optimization, with limited experience in remote
patient management. Due to the resource-intensive nature of
these procedures, we investigated a way to simplify
stimulation optimization for these patients that allows for
the continuous monitoring of symptoms while also reducing
patient burden and travel distances. To this end, we
prospectively recruited ten patients treated with DBS for PD
to evaluate the feasibility of telemedicinal optimization in
a home-based setting. Patients recorded daily videos of a
modified Unified Parkinson's Disease Rating Scale (UPDRS)
III, which experienced DBS physicians located at the clinic
assessed to provide instructions on adjusting stimulation
settings using a handheld programmer with previously set
programs as well as patient amplitude control. This study
concluded with significant improvements in participants'
motor status as measured by the UPDRS-III (p = 0.0313)
compared to baseline values. These findings suggest that
remote video-guided optimization of DBS settings is feasible
and may enhance motor outcomes for patients.Keywords:
home-based treatment; remote treatment; telemedicine.},
cin = {INM-3},
ddc = {570},
cid = {I:(DE-Juel1)INM-3-20090406},
pnm = {5251 - Multilevel Brain Organization and Variability
(POF4-525)},
pid = {G:(DE-HGF)POF4-5251},
typ = {PUB:(DE-HGF)16},
pubmed = {39335409},
UT = {WOS:001323876100001},
doi = {10.3390/brainsci14090914},
url = {https://juser.fz-juelich.de/record/1032448},
}