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@ARTICLE{Rttgen:1033924,
author = {Röttgen, Sinah and Doppler, Christopher E. J. and Seger,
Aline and Kalbe, Elke and Fink, Gereon Rudolf and
Sommerauer, Michael and Ophey, Anja},
title = {{C}ontext-dependency of the {REM} sleep behavior disorder
screening questionnaire - {C}linical utility under scrutiny},
journal = {Parkinsonism $\&$ related disorders},
volume = {130},
issn = {1353-8020},
address = {Amsterdam [u.a.]},
publisher = {Elsevier Science},
reportid = {FZJ-2024-06762},
pages = {107211 -},
year = {2025},
abstract = {AbstractIntroduction: The REM Sleep Behavior Disorder (RBD)
Screening Questionnaire (RBDSQ) is a widely established
screening tool for detecting isolated RBD (iRBD). However,
its accuracy may depend on its application context, e.g.,
the individuals' awareness of their RBD status. The present
work aims to describe the context-dependency and retest
reliability of the RBDSQ in an iRBD cohort setting.Methods:
Ninety-four individuals with video-polysomnography confirmed
iRBD answered the RBDSQ during pre-polysomnography screening
(V0) and post-diagnosis (V1).Results: The RBDSQ total score
significantly differed between V0 and V1 (F(1,92) = 8.02, p
= .006, ηp2 = 0.019). The intraclass correlation
coefficient (ICC2,1) of the RBDSQ showed moderate
reliability between consecutive timepoints (V0-V1ICC2,1 =
0.544). The highest Cohen's κ was reached for items 5, 6.3,
6.4, 8, and 9 across timepoint comparisons (0.409 ≤
Cohen's κ ≤ 0.660).Conclusion: Our findings underscore
the context-dependency of the RBDSQ and fluctuations in
self-awareness of sleep-related behaviors, necessitating a
critical appraisal of questionnaire-based RBD screening
tools. Future studies should explore strategies to improve
the reliability and accuracy of RBD screening tools,
considering the dynamic nature of sleep-related
behavior.Keywords: Disease awareness; REM sleep behavior
disorder; Reliability; Screening questionnaire.},
cin = {INM-3},
ddc = {610},
cid = {I:(DE-Juel1)INM-3-20090406},
pnm = {5252 - Brain Dysfunction and Plasticity (POF4-525) / DFG
project G:(GEPRIS)491111487 - Open-Access-Publikationskosten
/ 2022 - 2024 / Forschungszentrum Jülich (OAPKFZJ)
(491111487)},
pid = {G:(DE-HGF)POF4-5252 / G:(GEPRIS)491111487},
typ = {PUB:(DE-HGF)16},
pubmed = {39608327},
UT = {WOS:001369003400001},
doi = {10.1016/j.parkreldis.2024.107211},
url = {https://juser.fz-juelich.de/record/1033924},
}