| Home > Publications database > Etablierung von Zell- und Gewebekulturen für Medizinalpflanzen am Beispiel von Arnica montana im Rahmen des Projekts „Circular PhytoREVIER“ – Integrierte Wertschöpfung mit Anbau und Verwertung von Medizinalpflanzen im Rheinischen Revier |
| Contribution to a conference proceedings/Contribution to a book | FZJ-2024-06864 |
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2023
Bundesbehörden und Einrichtungen im Geschäftsbereich des Bundesministeriums für Ernährung und Landwirtschaft (BMEL)
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Please use a persistent id in citations: doi:10.5073/20230821-142037-0
Abstract: Developing sustainable cultivation methods for medicinal plants to meet the growing demand for high-quality raw materials is of great importance to the pharmaceutical industry. At the same time, it is important to minimize environmental impact and protect biodiversity. As part of the BioeconomyREVIER initiative to manage the structural change resulting from the phase-out of lignite, the Rhenish mining area is to be developed into a model region for a sustainable bioeconomy. To this end, projects are being supported in which innovative solutions are developed and implemented in the form of innovation labs through close cooperation between science and industry. One example is the “Circular PhytoREVIER“ project, which focuses on sustainable value creation with medicinal plants in the Rhenish mining area. The three scientific partners involved, Fraunhofer IME, Fraunhofer UMSICHT and Forschungszentrum Jülich, IBG-2, have combined their respective expertise, resources, infrastructures and preliminary work to establish yield- and location-optimized medicinal plants and to cultivate them both in the field and in closed indoor systems. We develop innovative methods for the targeted control and increase of the active ingredient content through the application of biological, chemical and physical stresses as well as for the non-invasive determination of growth and harvest parameters. The work of the Fraunhofer IME in this context includes the development of molecular markers for breeding and the generation of cell and tissue cultures of selected medicinal plants. One of our model plants is Arnica montana, which produces sesquiterpene lactones (SL) as valuable compounds. Our work has initially focused on the identification of the previously unknown SL biosynthetic genes and, in the future, on their characterization. For this purpose, we are currently focusing on the establishment of in vitro propagation of arnica plants, as well as plant regeneration from single cells, and finally on the genetic modification of Arnica montana in order to be able to characterize the biosynthetic genes of the SL metabolism in the future and to optimize the SL content in the plant or in cell culture.
Keyword(s): Medizinalpflanzen ; Bioökonomie ; Genomeditierung ; nicht-invasive Sensorik ; Pflanzenphänotypisierung ; Zell- und Gewebekulturen ; Pflanzentransformation ; medicinal plants ; bioeconomy ; genome editing ; non-invasive sensors ; plant phenotyping ; cell and tissue culture ; plant transformation ; 630
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